Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 4/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 6/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4761014 | 0.98 | ENPEP (0.37) | ENPEPMTNR1AMTNR1BALDH1A1ACACB | |
| SCHEMBL6569603 | 0.96 | ENPEP (0.36) | ENPEPMTNR1AMTNR1BALDH1A1ACACB | |
| SCHEMBL20149719 | 0.82 | PLA2G2C (0.45) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL11693818 | 0.79 | TGFBR1 (0.44) | ENPEP | |
| SCHEMBL6570305 | 0.78 | MTNR1A (0.34) | ENPEPMTNR1AMTNR1BALDH1A1ACACB | |
| SCHEMBL6569599 | 0.78 | MTNR1A (0.34) | ENPEPMTNR1AMTNR1BALDH1A1ACACB | |
| SCHEMBL4760783 | 0.77 | PLA2G2C (0.42) | ENPEPACACB | |
| SCHEMBL11860565 | 0.77 | MTNR1A (0.38) | MTNR1AMTNR1BALDH1A1ACACB | |
| SCHEMBL3210920 | 0.76 | ENPEP (0.33) | ENPEPALDH1A1TRPV1 | |
| SCHEMBL16979552 | 0.76 | ENPEP (0.43) | ENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265437-B1 | ALCOHOLISM | LIPHA (FR) | 2001-07-24 | — | — | US | claimed |
| CN-1182837-C | Orally administrable immediate and prolonged-release Galenic form comprising absorption-promoting agent and use of this absorption-promoting agent | Ĭ��ר���ɷ�����˾ | 2005-01-05 | — | — | CN | disclosed |
| EP-1056445-B1 | ORALLY ADMINISTRABLE IMMEDIATE-RELEASE AND PROLONGED-RELEASE GALENIC FORM COMPRISING AN ABSORPTION-PROMOTING AGENT AND USE OF THIS ABSORPTION-PROMOTING AGENT | MERCK PATENT GMBH (DE) | 2004-06-02 | — | — | EP | disclosed |
| EP-1410791-A1 | Orally administrable galenic form comprising metformine and an absorption-promoting agent | MERCK PATENT GmbH (DE) | 2004-04-21 | — | — | EP | disclosed |
| US-6514524-B1 | Improved absorption of hydrophilic ingredients because of particular excipients; calcium 3-acetylamino-1-propane sulfonate (calcium acamprosate); polysorbates, fatty ethers or esters of PEG, polyglycolysed glycerides | MERCK PATENTGESELLSCHAFT MIT (DE) | 2003-02-04 | — | — | US | disclosed |
| US-6426087-B1 | GALENIC FORMS; SUSTAINED RELEASE | MERCK PATENT GESELLSCHAFT MIT (DE) | 2002-07-30 | — | — | US | disclosed |
| US-6265437-B1 | ALCOHOLISM | LIPHA (FR) | 2001-07-24 | — | — | US | disclosed |