SCHEMBL476137

SCHEMBL476137

C[Si](C)CCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
CASP1 P29466 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TAAR1 Q96RJ0 3/20 0.46
ATM Q13315 1/20 0.46
TDP1 Q9NUW8 2/20 0.46
CYP2A6 P11509 1/20 0.46
HTR2A P28223 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
TP53 P04637 1/20 0.43
AOC3 Q16853 1/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
KCNH2 Q12809 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL476047 0.85 L3MBTL1 (0.48) HTR2AAOC3MAOAMAOBL3MBTL1
SCHEMBL2803696 0.83 MAOA (0.52) MAOAMAOBL3MBTL1
SCHEMBL17386494 0.78 ALDH1A1 (0.52) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL3736315 0.75 CA1 (0.35) TAAR1CYP2A6
SCHEMBL7105335 0.75 ESR1 (0.59) ALDH1A1HSD17B10TAAR1TDP1TP53
SCHEMBL5477947 0.74 ALDH1A1 (0.48) ALDH1A1HPGDALOX15ALOX12CASP1
Ethane SCHEMBL21049496 0.74 ALDH1A1 (0.61) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL62125 0.73 ALDH1A1 (0.69) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL9741303 0.73 ALDH1A1 (0.69) ALDH1A1HPGDALOX15ALOX12CASP1
Benzene SCHEMBL3440179 0.73 ALDH1A1 (0.69) ALDH1A1HPGDALOX15ALOX12CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406468-B Silicone-modified photoinitiators and photocurable adhesive compositions thereof 汉高股份有限及两合公司 2020-11-06 CN claimed
EP-3186263-B1 ORGANOSILICON MODIFIED PHOTOINITIATOR AND PHOTO-CURABLE ADHESIVE COMPOSITION THEREOF HENKEL AG & CO KGAA (DE) 2020-04-22 EP claimed
US-10189867-B2 Organosilicon modified photoinitiator and a photo-curable adhesive composition comprising the same Henkel IP & Holding GmbH (DE) 2019-01-29 US claimed
EP-3186263-A1 ORGANOSILICON MODIFIED PHOTOINITIATOR AND PHOTO-CURABLE ADHESIVE COMPOSITION THEREOF Henkel AG & Co. KGaA (DE) 2017-07-05 EP claimed
US-20170166594-A1 Organosilicon modified photoinitiator and a photo-curable adhesive composition comprising the same HENKEL (CHINA) COMPANY LIMITED (CN) 2017-06-15 US claimed
WO-2016029439-A1 ORGANOSILICON MODIFIED PHOTOINITIATOR AND PHOTO-CURABLE ADHESIVE COMPOSITION THEREOF HENKEL (CHINA) COMPANY LIMITED (CN) 2016-03-03 WO claimed
EP-4234643-A2 ANTIFOULING COMPOSITION Jotun A/S (NO) 2023-08-30 EP disclosed
CN-108070055-B Antifouling composition 佐敦公司 2022-10-04 CN disclosed
CN-108070054-B Anti-fouling composition 佐敦公司 2022-05-03 CN disclosed
CN-109983083-B Antifouling composition 佐敦有限公司 2021-08-17 CN disclosed
CN-106047173-B Antifouling composition 佐敦集团 2020-12-11 CN disclosed
CN-107406468-B Silicone-modified photoinitiators and photocurable adhesive compositions thereof 汉高股份有限及两合公司 2020-11-06 CN disclosed
CN-106146851-B Photocurable composition and cured product containing same 信越化学工业株式会社 2020-10-23 CN disclosed
CN-1189830-A Substituted 1, 3-dioxan-5-ylamino-heterocyclic compounds, method for the production thereof and use thereof as pest control agents HOECHST SCHERING AGREVO GMBH (DE) 1998-08-05 CN disclosed
CN-1161037-A Substituted spiroalkylamino and spiroalkoxy heterocycles, process for their preparation and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1997-10-01 CN disclosed
US-5625078-A Processes for the production of 13-ether derivatives of milbemycins and novel intermediates therefor SANKYO COMPANY, LIMITED (JP) 1997-04-29 US disclosed
CN-1148383-A Heterocyclylamino-and heterocyclyloxy-cycloalkyl derivatives, their preparation and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1997-04-23 CN disclosed
US-5461168-A Processes for the production of 13-ether derivatives of milbemycins, and intermediates therefor SANKYO COMPANY, LIMITED (JP) 1995-10-24 US disclosed
EP-0594291-A1 Novel processes for the production of 13-ether derivatives of milbemycins, and novel intermediates therefor SANKYO COMPANY LIMITED (JP) 1994-04-27 EP disclosed
US-4656221-A SOLVENT-FREE POLYSILOXANE COATINGS; RADIATION TRANSPARENT FOR USE ON COLORLESS BEVERAGE BOTTLES TOSHIBA SILICONE CO., LTD. (JP) 1987-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10189867-B2 Organosilicon modified photoinitiator and a photo-curable adhesive composition comprising the same ITGB2, ITGB8, C3AR1 ALDH1A1 1399/4885HPGD 4528/4885ALOX15 1945/4885
US-20170166594-A1 Organosilicon modified photoinitiator and a photo-curable adhesive composition comprising the same ITGB2, ITGB8, C3AR1 ALDH1A1 1378/4885HPGD 4507/4885ALOX15 2027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.