SCHEMBL476047

SCHEMBL476047

C[Si](C)CCCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
SIGMAR1 Q99720 5/20 0.48
MAOA P21397 1/20 0.48
CHRM2 P08172 1/20 0.47
HTR1A P08908 1/20 0.47
ADRA2A P08913 1/20 0.47
CHRM1 P11229 1/20 0.47
DRD1 P21728 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
ADRA1A P35348 1/20 0.47
OPRM1 P35372 1/20 0.47
DRD3 P35462 1/20 0.47
SLC6A3 Q01959 1/20 0.47
KCNH2 Q12809 1/20 0.47
AOC3 Q16853 1/20 0.47
MAOB P27338 1/20 0.46
HTR2A P28223 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2803696 0.93 MAOA (0.52) L3MBTL1MEN1KMT2ASIGMAR1MAOA
SCHEMBL476137 0.85 ALDH1A1 (0.48) L3MBTL1MAOAKCNH2AOC3MAOB
Water SCHEMBL27582857 0.83 ALDH1A1 (0.46) L3MBTL1MAOAAOC3MAOBHTR2A
SCHEMBL17386451 0.80 SIGMAR1 (0.52) L3MBTL1SIGMAR1MAOAADRA1ASLC6A3
SCHEMBL17444461 0.80 MEN1 (0.43) MEN1KMT2AMAOBHTR2A
SCHEMBL7712816 0.76 SIGMAR1 (0.48) L3MBTL1SIGMAR1MAOAADRA1ASLC6A3
SCHEMBL54347 0.76 HTR2A (0.70) SIGMAR1MAOAADRA1ASLC6A3MAOB
SCHEMBL451456 0.76 MAOA (0.74) L3MBTL1SIGMAR1MAOAMAOBHTR2A
SCHEMBL676854 0.73 SIGMAR1 (0.71) L3MBTL1SIGMAR1MAOAMAOB
SCHEMBL8094527 0.73 SIGMAR1 (0.71) L3MBTL1SIGMAR1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104546561-A Three-dimensional molding wax oil powder and preparation method thereof LIXIN BIOTECH COSMETIC SHANGHAI CO LTD 2015-04-29 CN claimed
WO-2023208316-A1 CYCLODEXTRIN INCORPORATED SILICONE MATERIALS AND THEIR USE AS CARRIERS FOR ACTIVES WACKER CHEMIE AG (DE) 2023-11-02 WO disclosed
EP-4234643-A2 ANTIFOULING COMPOSITION Jotun A/S (NO) 2023-08-30 EP disclosed
US-20230096721-A1 METAL-ORGANIC FRAMEWORK WITH CARBOXYLIC ACID ION HAVING TERPHENYL SKELETON AS LIGAND RIKKYO EDUCATIONAL CORPORATION (JP) 2023-03-30 US disclosed
US-20230056785-A1 GAS-STORING MATERIAL INCLUDING METAL/ORGANIC FRAMEWORK BONDED BY HYDROXAMIC ACID RIKKYO EDUCATIONAL CORPORATION (JP) 2023-02-23 US disclosed
EP-4112595-A1 METAL-ORGANIC FRAMEWORK WITH CARBOXYLIC ACID ION HAVING TERPHENYL SKELETON AS LIGAND Rikkyo Educational Corporation (JP) 2023-01-04 EP disclosed
US-20220410120-A1 HYDROGEN STORAGE MATERIAL CONTAINING METAL ORGANIC STRUCTURE RIKKYO EDUCATIONAL CORPORATION (JP) 2022-12-29 US disclosed
US-20220401916-A1 METAL-ORGANIC FRAMEWORK HAVING TEREPHTHALIC ACID BASED LIGAND RIKKYO EDUCATIONAL CORPORATION (JP) 2022-12-22 US disclosed
CN-108070055-B Antifouling composition 佐敦公司 2022-10-04 CN disclosed
CN-115151523-A Metal-organic structure having carboxylate ion having terphenyl skeleton as ligand 学校法人立教学院 2022-10-04 CN disclosed
US-7825103-B2 5'-O-triisopropylsilyl-2'-cyano-2'-deoxy-1- beta -D-arabinofuranosylcytosine; antitumor agents TAIHO PHARMACEUTICAL CO., LTD. (JP) 2010-11-02 US disclosed
EP-2173780-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER Jotun A/S (NO) 2010-04-14 EP disclosed
WO-2009149919-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN A/S (NO) 2009-12-17 WO disclosed
US-20090306008-A1 3'-ETHYNYLCYTIDINE DERIVATIVE Sasaki, Takuma (JP) 2009-12-10 US disclosed
CN-101490076-A 3' -ethynylcytosine nucleoside derivatives TAIHO PHARMACEUTICAL CO LTD (JP) 2009-07-22 CN disclosed
US-20090118222-A1 NOVEL PYRIMIDINE NUCLEOSIDE COMPOUND OR ITS SALT TAIHO PHARMACEUTICAL CO., LTD. (JP) 2009-05-07 US disclosed
EP-2045258-A1 3'-ETHYNYLCYTIDINE DERIVATIVE Taiho Pharmaceutical Co., Ltd. (JP) 2009-04-08 EP disclosed
WO-2009007276-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN A/S (NO) 2009-01-15 WO disclosed
CN-101111509-A Novel pyrimidine nucleoside compound or salt thereof TAIHO PHARMACEUTICAL CO LTD (JP) 2008-01-23 CN disclosed
EP-1845102-A1 NOVEL PYRIMIDINE NUCLEOSIDE COMPOUND OR ITS SALT TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 2007-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090118222-A1 NOVEL PYRIMIDINE NUCLEOSIDE COMPOUND OR ITS SALT CDK10, SRSF9, SNRPD1 L3MBTL1 1019/4885MEN1 2140/4885KMT2A 3710/4885
US-20230096721-A1 METAL-ORGANIC FRAMEWORK WITH CARBOXYLIC ACID ION HAVING TERPHENYL SKELETON AS LIGAND SCO2, SLCO2A1, OXGR1 L3MBTL1 666/4885MEN1 1025/4885KMT2A 2353/4885
US-20090306008-A1 3'-ETHYNYLCYTIDINE DERIVATIVE SLC7A1, SLC29A1, SLC26A3 L3MBTL1 2487/4885MEN1 1544/4885KMT2A 2031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.