SCHEMBL476156

SCHEMBL476156

CC[C@H](C)[C@H](N)C(=O)N(C)OC

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 15/20 0.40
DPP8 Q6V1X1 8/20 0.40
DPP9 Q86TI2 7/20 0.40
FAAH O00519 1/20 0.38
DPP7 Q9UHL4 7/20 0.36
IARS1 P41252 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28004804 1.00 DPP4 (0.40) DPP4DPP8DPP9FAAHDPP7
SCHEMBL28074283 0.85 ALDH1A1 (0.39) DPP4DPP8DPP9FAAH
SCHEMBL12877425 0.80 FAAH (0.40) FAAH
SCHEMBL12171866 0.80 FAAH (0.40) FAAH
SCHEMBL7276777 0.79 DPP4 (0.46) DPP4DPP8DPP9FAAHDPP7
SCHEMBL4595829 0.79 DPP4 (0.44) DPP4DPP8DPP9DPP7
SCHEMBL22952874 0.79 DPP4 (0.46) DPP4DPP8DPP9FAAHDPP7
SCHEMBL7276787 0.79 DPP4 (0.46) DPP4DPP8DPP9FAAHDPP7
SCHEMBL6628997 0.78 FAAH (0.38) DPP4DPP9FAAH
SCHEMBL6629003 0.78 FAAH (0.38) DPP4DPP9FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260055150-A1 GRAIL-1 PEPTIDE PRODUCTS AND METHODS UNIV MICHIGAN (US) 2026-02-26 US disclosed
EP-4680108-A1 PEPTIDE MULTIMER PRODUCTS AND METHODS The Regents of The University of Michigan (US) 2026-01-21 EP disclosed
US-20250263439-A1 HETERODIMERIC PEPTIDE REAGENTS AND METHODS THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-08-21 US disclosed
EP-3660040-B1 INSULIN RECEPTOR PARTIAL AGONISTS MERCK SHARP & DOHME LLC (US) 2025-06-18 EP disclosed
EP-4565333-A2 GRAIL-1 PEPTIDE PRODUCTS AND METHODS Regents of the University of Michigan (US) 2025-06-11 EP disclosed
US-12269900-B2 Inhibitors of β integrin-G protein α subunit binding interactions THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2025-04-08 US disclosed
US-20250073355-A1 CD44-BINDING PEPTIDE REAGENTS AND METHODS REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-03-06 US disclosed
US-20250051416-A1 INSULIN RECEPTOR PARTIAL AGONISTS MERCK SHARP & DOHME LLC (US) 2025-02-13 US disclosed
WO-2025006976-A2 MRNA DISPLAY LIBRARIES AND METHODS OF USE THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2025-01-02 WO disclosed
EP-3666792-B1 INSULIN RECEPTOR PARTIAL AGONISTS MERCK SHARP & DOHME LLC (US) 2024-12-18 EP disclosed
WO-2011075393-A2 GLUCAGON/GLP-1 RECEPTOR CO-AGONISTS INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2011-06-23 WO disclosed
EP-2307037-A1 GLUCAGON ANALOGS EXHIBITING ENHANCED SOLUBILITY AND STABILITY IN PHYSIOLOGICAL PH BUFFERS Indiana University Research and Technology Corporation (US) 2011-04-13 EP disclosed
EP-2300037-A2 GLUCAGON/GLP-1 RECEPTOR CO-AGONISTS Indiana University Research and Technology Corporation (US) 2011-03-30 EP disclosed
EP-2300035-A2 GIP-BASED MIXED AGONISTS FOR TREATMENT OF METABOLIC DISORDERS AND OBESITY Indiana University Research and Technology Corporation (US) 2011-03-30 EP disclosed
WO-2010148089-A1 GIP RECEPTOR-ACTIVE GLUCAGON COMPOUNDS INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2010-12-23 WO disclosed
WO-2010111617-A2 PARATHYROID HORMONE PEPTIDES AND PARATHYROID HORMONE-RELATED PROTEIN PEPTIDES AND METHODS OF USE VAN ANDEL RESEARCH INSTITUTE (US) 2010-09-30 WO disclosed
WO-2010071807-A1 AMIDE BASED GLUCAGON SUPERFAMILY PEPTIDE PRODRUGS INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2010-06-24 WO disclosed
WO-2010011439-A2 GIP-BASED MIXED AGONISTS FOR TREATMENT OF METABOLIC DISORDERS AND OBESITY INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2010-01-28 WO disclosed
WO-2009155258-A2 GLUCAGON/GLP-1 RECEPTOR CO-AGONISTS INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2009-12-23 WO disclosed
WO-2009155257-A1 GLUCAGON ANALOGS EXHIBITING ENHANCED SOLUBILITY AND STABILITY PHYSIOLOGICAL PH BUFFERS INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2009-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055150-A1 GRAIL-1 PEPTIDE PRODUCTS AND METHODS TP53, TP53BP1, DDIT3 DPP4 4410/4885DPP8 3817/4885DPP9 4307/4885
US-20250263439-A1 HETERODIMERIC PEPTIDE REAGENTS AND METHODS ERBB2, EGFR, ERBB3 DPP4 3631/4885DPP8 2927/4885DPP9 2291/4885
US-20250051416-A1 INSULIN RECEPTOR PARTIAL AGONISTS INSR, GPR119, IRS1 DPP4 262/4885DPP8 221/4885DPP9 396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.