Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1207015 | 0.71 | L3MBTL1 (0.42) | GAAMEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL2419571 | 0.68 | GAA (1.00) | GAAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL23398990 | 0.66 | GAA (0.56) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL565193 | 0.66 | ALOX15 (0.77) | GAAMEN1ALOX15KMT2AHSD17B10 | |
| SCHEMBL7803870 | 0.65 | MAPT (0.46) | GAAMEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL27731657 | 0.64 | USP7 (0.60) | GAAMEN1ALOX15KMT2AHSD17B10 | |
| SCHEMBL16872782 | 0.64 | GAA (0.53) | GAAMEN1ALOX15KMT2AKDM4E | |
| SCHEMBL653071 | 0.63 | TDP1 (0.74) | GAAMEN1ALOX15KMT2AHSD17B10 | |
| SCHEMBL30392415 | 0.63 | TDP1 (0.74) | GAAMEN1ALOX15KMT2AHSD17B10 | |
| SCHEMBL27829121 | 0.63 | TDP1 (0.74) | GAAMEN1ALOX15KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904452-A2 | HISTONE DEACETYLASE INHIBITORS | Takeda San Diego, Inc. (US) | 2008-04-02 | — | — | EP | claimed |
| WO-2007011626-A2 | HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2007-01-25 | — | — | WO | claimed |