Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.64 |
| ▸ | IKBKB | O14920 | 1/20 | 0.55 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.53 |
| ▸ | HNF4A | P41235 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20945278 | 0.91 | ALOX15 (0.94) | ALOX15HSD17B10CYP3A4KDM4EMEN1 | |
| SCHEMBL30313807 | 0.91 | ALOX15 (0.94) | ALOX15HSD17B10CYP3A4KDM4EMEN1 | |
| SCHEMBL16949848 | 0.88 | ALOX15 (0.81) | ALOX15HSD17B10CYP3A4KDM4EMEN1 | |
| SCHEMBL29488305 | 0.88 | ALOX15 (0.81) | ALOX15HSD17B10CYP3A4KDM4EMEN1 | |
| SCHEMBL29228667 | 0.88 | ALOX15 (0.81) | ALOX15HSD17B10CYP3A4KDM4EMEN1 | |
| SCHEMBL23924225 | 0.88 | CYP3A4 (1.00) | ALOX15HSD17B10CYP3A4KDM4EMEN1 | |
| SCHEMBL29365557 | 0.88 | CYP3A4 (1.00) | ALOX15HSD17B10CYP3A4KDM4EMEN1 | |
| SCHEMBL29549758 | 0.88 | CYP3A4 (1.00) | ALOX15HSD17B10CYP3A4KDM4EMEN1 | |
| SCHEMBL105866 | 0.88 | CYP3A4 (1.00) | ALOX15HSD17B10CYP3A4KDM4EMEN1 | |
| Methane SCHEMBL3324869 | 0.85 | CYP3A4 (0.94) | ALOX15HSD17B10CYP3A4KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 675 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12383482-B2 | Hair coloring compositions | WELLA GERMANY GMBH (DE) | 2025-08-12 | — | — | US | claimed |
| EP-4251285-B1 | HAIR COLORING COMPOSITIONS | WELLA INT OPERATIONS SWITZERLAND SARL (CH) | 2024-09-04 | — | — | EP | claimed |
| US-20240024218-A1 | HAIR COLORING COMPOSITIONS | WELLA GERMANY GMBH (DE) | 2024-01-25 | — | — | US | claimed |
| CN-117396185-A | Hair dyeing composition | 威娜国际运营瑞士责任有限公司 | 2024-01-12 | — | — | CN | claimed |
| EP-4251285-A1 | HAIR COLORING COMPOSITIONS | Wella International Operations Switzerland Sàrl (CH) | 2023-10-04 | — | — | EP | claimed |
| WO-2022112473-A1 | HAIR COLORING COMPOSITIONS | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2022-06-02 | — | — | WO | claimed |
| CN-104114540-B | 1-hexyl-1H-pyrazoles-4,5-diamidogen Hemisulphate and the purposes in colouring compositions thereof | 宝洁公司 | 2016-06-22 | — | — | CN | claimed |
| US-9060953-B2 | 1-hexyl-1H-pyrazole-4,5-diamine hemisulfate, and its use in dyeing compositions | THE PROCTER & GAMBLE COMPANY (US) | 2015-06-23 | — | — | US | claimed |
| CN-104114540-A | 1-HEXYL-1H-PYRAZOLE-4,5-DIAMINE HEMISULFATE, AND ITS USE IN DYEING COMPOSITIONS | PROCTER & GAMBLE | 2014-10-22 | — | — | CN | claimed |
| US-20140289973-A1 | 1-Hexyl-1H-Pyrazole-4,5-Diamine Hemisulfate, and Its Use in Dyeing Compositions | WELLA OPERATIONS US, LLC | 2014-10-02 | — | — | US | claimed |
| US-20130212810-A1 | 1-Hexzl-1H-Pyrazole-4,5-Diamine Hemisulfate, and Its Use in Dyeing Compositions | THE PROCTER & GAMBLE COMPANY (US) | 2013-08-22 | — | — | US | claimed |
| WO-2013122990-A1 | 1-HEXYL-1H-PYRAZOLE-4,5-DIAMINE HEMISULFATE, AND ITS USE IN DYEING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2013-08-22 | — | — | WO | claimed |
| EP-2628731-A1 | 1-Hexyl-1H-pyrazole-4,5-diamine hemisulfate, and its use in dyeing compositions | The Procter and Gamble Company (US) | 2013-08-21 | — | — | EP | claimed |
| EP-1752192-B1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | PROCTER & GAMBLE (US) | 2010-02-03 | — | — | EP | claimed |
| US-7122061-B2 | Agents for dyeing keratin fibers, containing 4-aminobiphenyl-3-ol-derivatives | WELLA AG (DE) | 2006-10-17 | — | — | US | claimed |
| US-20060004180-A1 | Solution compositions of block copolyimides comprising pyromellitic dianhydride and process for production thereof | PI R&D CO., LTD. (JP) | 2006-01-05 | — | — | US | claimed |
| EP-1562539-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2005-08-17 | — | — | EP | claimed |
| EP-1561786-A1 | SOLUTION COMPOSITIONS OF BLOCK COPOLYIMIDES COMPRISING PYROMELLITIC DIANHYDRIDE AND PROCESS FOR PRODUCTION THEREOF | PI R & D Co., Ltd. (JP) | 2005-08-10 | — | — | EP | claimed |
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2005-07-21 | — | — | US | claimed |
| WO-2004041226-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-05-21 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140289973-A1 | 1-Hexyl-1H-Pyrazole-4,5-Diamine Hemisulfate, and Its Use in Dyeing Compositions | PPOX, XDH, DPYD | ALOX15 2190/4885HSD17B10 1757/4885CYP3A4 208/4885 |
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | KRT18, CBR3, CCNB3 | ALOX15 3006/4885HSD17B10 913/4885CYP3A4 835/4885 |
| US-20130212810-A1 | 1-Hexzl-1H-Pyrazole-4,5-Diamine Hemisulfate, and Its Use in Dyeing Compositions | PPOX, XDH, TYR | ALOX15 1105/4885HSD17B10 1973/4885CYP3A4 282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.