Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14110955 | 0.86 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL3322371 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL4227750 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL4655115 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL9499751 | 0.78 | LMNA (0.56) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL14383794 | 0.77 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL13832433 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL12643251 | 0.76 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL4206714 | 0.76 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL16385539 | 0.75 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852414-B1 | Process for the preparation of 4-Hydroxyalkylamino-2-nitro-anisoles | WELLA AG (DE) | 2008-11-26 | — | — | EP | disclosed |