SCHEMBL4762074

SCHEMBL4762074

CC(C)(O)C(=O)c1ccc(OCCN)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 10/20 0.48
ESR1 P03372 9/20 0.48
ESR2 Q92731 9/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CYP3A4 P08684 3/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2A6 P11509 2/20 0.47
CYP3A5 P20815 2/20 0.47
CYP2D6 P10635 1/20 0.47
MAPT P10636 2/20 0.46
GAA P10253 1/20 0.46
TAAR1 Q96RJ0 1/20 0.44
PARP10 Q53GL7 1/20 0.44
LTA4H P09960 1/20 0.43
PLA2G2A P14555 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20521381 0.98 SMN1; SMN2 (0.50) CYP19A1ESR1ESR2SMN1; SMN2L3MBTL1
SCHEMBL24161906 0.85 MAPT (0.49) CYP19A1ESR1ESR2SMN1; SMN2L3MBTL1
SCHEMBL10713224 0.85 TP53 (0.58) SMN1; SMN2L3MBTL1GAA
SCHEMBL36443 0.85 GAA (0.56) SMN1; SMN2L3MBTL1CYP3A4MAPTGAA
SCHEMBL402554 0.85 L3MBTL1 (0.58) L3MBTL1MAPTGAA
SCHEMBL15828758 0.83 MAPT (0.54) L3MBTL1MAPTGAAPARP10
SCHEMBL3975588 0.83 L3MBTL1 (0.47) L3MBTL1MAPTGAAPARP10
SCHEMBL11927404 0.83 L3MBTL1 (0.51) L3MBTL1MAPTGAA
SCHEMBL19998344 0.83 PKM (0.64) L3MBTL1MAPTGAAPARP10
SCHEMBL28651564 0.83 GAA (0.54) SMN1; SMN2L3MBTL1CYP3A4MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0495011-A4 HYDROPHILIC POLYURETHANE ELASTOMERS 1992-08-12 EP claimed
EP-0495011-A1 HYDROPHILIC POLYURETHANE ELASTOMERS PolyMedica Industries, Inc. (US) 1992-07-22 EP claimed
US-5118779-A Drug delivery POLYMEDICA INDUSTRIES, INC. (US) 1992-06-02 US claimed
US-5045573-A Alkanophenones MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-09-03 US claimed
WO-1991005809-A1 HYDROPHILIC POLYURETHANE ELASTOMERS POLYMEDICA INDUSTRIES, INC. (US) 1991-05-02 WO claimed
EP-0216884-B1 PHOTO-INITIATOR FOR THE PHOTO-POLYMERIZATION OF UNSATURATED SYSTEMS MERCK PATENT GmbH (DE) 1990-08-08 EP claimed
US-12070531-B2 Polymeric coatings COLOPLAST A/S (DK) 2024-08-27 US disclosed
EP-3668555-B2 POLYMERIC COATINGS COLOPLAST AS (DK) 2024-07-24 EP disclosed
US-11685708-B2 Acrylamide photoinitiators COLOPLAST A/S (DK) 2023-06-27 US disclosed
US-11685708-B2 Acrylamide photoinitiators COLOPLAST A/S (DK) 2023-06-27 US disclosed
US-11685708-B2 Acrylamide photoinitiators COLOPLAST A/S (DK) 2023-06-27 US disclosed
EP-3668906-B1 AMIDE AND IMIDE PHOTOINITIATORS COLOPLAST AS (DK) 2023-06-07 EP disclosed
EP-3668906-B1 AMIDE AND IMIDE PHOTOINITIATORS COLOPLAST AS (DK) 2023-06-07 EP disclosed
US-5045573-A Alkanophenones MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-09-03 US disclosed
WO-1991005809-A1 HYDROPHILIC POLYURETHANE ELASTOMERS POLYMEDICA INDUSTRIES, INC. (US) 1991-05-02 WO disclosed
EP-0216884-B1 PHOTO-INITIATOR FOR THE PHOTO-POLYMERIZATION OF UNSATURATED SYSTEMS MERCK PATENT GmbH (DE) 1990-08-08 EP disclosed
US-4861916-A Photoinitiators for photopolymerization of unsaturated systems MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-08-29 US disclosed
EP-0281941-A2 Coreactive photoinitiators CIBA-GEIGY AG (CH) 1988-09-14 EP disclosed
EP-0216884-A1 PHOTO-INITIATOR FOR THE PHOTO-POLYMERIZATION OF UNSATURATED SYSTEMS. MERCK PATENT GMBH (DE) 1987-04-08 EP disclosed
WO-1986005777-A1 PHOTO-INITIATOR FOR THE PHOTO-POLYMERIZATION OF UNSATURATED SYSTEMS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11685708-B2 Acrylamide photoinitiators AAAS, ACR, CRYAA CYP19A1 976/4885ESR1 1935/4885ESR2 2755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.