Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14047364 | 0.79 | ALDH1A1 (0.36) | ALDH1A1PKMCTRCRAB9A | |
| SCHEMBL21845024 | 0.79 | ALDH1A1 (0.33) | ALDH1A1MCOLN3PKMKMT2ACYP2D6 | |
| SCHEMBL23836841 | 0.76 | CYP2C9 (0.35) | ALDH1A1MCOLN3PKM | |
| SCHEMBL19757591 | 0.75 | RIPK1 (0.39) | ALDH1A1KMT2APOLB | |
| SCHEMBL9367503 | 0.73 | GSTP1 (0.37) | ALDH1A1KMT2ACYP2D6CTRCCTRB1 | |
| SCHEMBL9367500 | 0.73 | GSTP1 (0.37) | ALDH1A1KMT2ACYP2D6CTRCCTRB1 | |
| SCHEMBL13435215 | 0.73 | SMN1; SMN2 (0.33) | ALDH1A1 | |
| SCHEMBL11625723 | 0.72 | RAB9A (0.50) | ALDH1A1MCOLN3PKMGAAKMT2A | |
| SCHEMBL15706250 | 0.72 | TAAR1 (0.42) | ALDH1A1KMT2ARAB9A | |
| SCHEMBL17499966 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MCOLN3PKMGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160317672-A1 | DERIVATIVE OF STYRENE-MALEIC ACID COPOLYMER | Maeda, Hiroshi (JP) | 2016-11-03 | — | — | US | disclosed |
| US-8932662-B2 | Coatings prepared from poly(ethylene oxide) and photo-initator-containing scaffolds | COLOPLAST A/S (DK) | 2015-01-13 | — | — | US | disclosed |
| US-20140363562-A1 | PHOTO-CURING OF THERMOPLASTIC COATINGS | COLOPLAST A/S (DK) | 2014-12-11 | — | — | US | disclosed |
| US-20130115466-A1 | PHOTO-CURING OF THERMOPLASTIC COATINGS | COLOPLAST A/S (DK) | 2013-05-09 | — | — | US | disclosed |
| US-20120121919-A1 | MEDICAL DEVICE OF POLYOLEFIN | COLOPLAST A/S (DK) | 2012-05-17 | — | — | US | disclosed |
| US-20100119833-A1 | PHOTO-CURING OF THERMOPLASTIC COATINGS | MADSEN NIELS JORGEN | 2010-05-13 | — | — | US | disclosed |
| US-4309335-A | THERMAL AGING RESISTANCE; ORTHO-SUBSTITUTED PHENYL ACID PHOSPHITE | ADEKA ARGUS CHEMICAL CO., LTD. | 1982-01-05 | — | — | US | disclosed |
| US-4122185-A | 2-Phenyl- and 2-benzyl-N-[(trichloromethyl)thio]succinimides, and fungicidal compositions thereof | STERLING DRUG INC. (US) | 1978-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160317672-A1 | DERIVATIVE OF STYRENE-MALEIC ACID COPOLYMER | ME3, SMN1; SMN2, SMC1A | ALDH1A1 174/4885MCOLN3 2168/4885PKM 1868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.