Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | BAX | Q07812 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4923326 | 0.74 | — | — | |
| SCHEMBL10320581 | 0.70 | BCAT2 (0.41) | LTA4HTSHRSOS1SMN1; SMN2NPC1 | |
| SCHEMBL2521152 | 0.69 | LTA4H (0.58) | LTA4HTSHRSMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL1680656 | 0.66 | LTA4H (0.60) | LTA4HTSHRSOS1SMN1; SMN2HTT | |
| SCHEMBL8941551 | 0.66 | PTGS2 (0.54) | SOS1SMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL7263349 | 0.65 | LTA4H (0.52) | LTA4HTSHRSOS1SMN1; SMN2HTT | |
| SCHEMBL3893562 | 0.65 | LTA4H (0.92) | LTA4HTSHRSOS1NPC1RAB9A | |
| SCHEMBL22129853 | 0.65 | LTA4H (0.92) | LTA4HTSHRSOS1NPC1RAB9A | |
| SCHEMBL122719 | 0.65 | LTA4H (0.92) | LTA4HTSHRSOS1NPC1RAB9A | |
| SCHEMBL11576945 | 0.65 | LTA4H (0.92) | LTA4HTSHRSOS1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552182-B2 | Method for producing a 3-(substituted-oxy)-4-pyridazinol derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2013-10-08 | — | — | US | disclosed |
| US-20120184736-A1 | METHOD FOR PRODUCING A 3-(SUBSTITUTED-OXY)-4-PYRIDAZINOL DERIVATIVE | MITSUI CHEMICALS AGRO, INC (JP) | 2012-07-19 | — | — | US | disclosed |
| JP-2008239532-A | METHOD FOR PRODUCING 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE | SANKYO AGRO KK | 2008-10-09 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184736-A1 | METHOD FOR PRODUCING A 3-(SUBSTITUTED-OXY)-4-PYRIDAZINOL DERIVATIVE | CYP4F3, CYP4F2, PNPO | LTA4H 1191/4885TSHR 1799/4885SOS1 4207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.