Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | GCK | P35557 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9987882 | 0.86 | GCK (0.47) | PTGS2PTGS1ALDH1A1GCK | |
| SCHEMBL8941703 | 0.85 | MEN1 (0.46) | PTGS2PTGS1 | |
| SCHEMBL7359540 | 0.85 | SOS1 (0.64) | PTGS2PTGS1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8941557 | 0.83 | MAPT (0.56) | PTGS2PTGS1LMNAKDM4EALDH1A1 | |
| SCHEMBL2521152 | 0.79 | LTA4H (0.58) | HTTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL10833881 | 0.79 | ADAMTS4 (0.53) | PTGS2PTGS1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8941611 | 0.79 | PTPRZ1 (0.46) | LMNAHTTSMN1; SMN2SOS1KDM4E | |
| SCHEMBL8941513 | 0.78 | HTT (0.57) | PTGS2PTGS1LMNAHTTSMN1; SMN2 | |
| SCHEMBL12327379 | 0.78 | ADAMTS4 (0.56) | PTGS2PTGS1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11547843 | 0.77 | HTT (0.58) | PTGS2PTGS1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | claimed |
| US-5480568-A | FOR LUBRICATING METAL CONTAINING SURFACES | THE DOW CHEMICAL COMPANY (US) | 1996-01-02 | — | — | US | disclosed |