Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762118 | 0.89 | SLC6A2 (0.36) | KMT2AMEN1 | |
| SCHEMBL7428804 | 0.75 | CPN1 (0.40) | — | |
| SCHEMBL4769131 | 0.75 | CPN1 (0.40) | — | |
| SCHEMBL4763256 | 0.75 | ALDH1A1 (0.45) | — | |
| SCHEMBL4763260 | 0.75 | ALDH1A1 (0.45) | — | |
| SCHEMBL4762115 | 0.70 | BDKRB2 (0.46) | — | |
| SCHEMBL4762112 | 0.70 | BDKRB2 (0.46) | — | |
| SCHEMBL3956512 | 0.69 | CTSK (0.40) | — | |
| SCHEMBL3956504 | 0.69 | CTSK (0.40) | — | |
| SCHEMBL4689601 | 0.68 | CTSK (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320370-A4 | METHOD OF TREATMENT | SMITHKLINE BEECHAM CORP (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1320370-A1 | METHOD OF TREATMENT | SmithKline Beecham Corporation (US) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002017924-A1 | METHOD OF TREATMENT | SMITHKLINE BEECHAM CORPORATION (GB) | 2002-03-07 | — | — | WO | disclosed |