Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 2/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428804 | 1.00 | CPN1 (0.40) | CPN1CPB2SLC6A1SLC6A11TSHR | |
| SCHEMBL6591619 | 0.83 | EPHX1 (0.42) | CPN1CPB2EPHX1 | |
| SCHEMBL4763263 | 0.75 | KMT2A (0.37) | — | |
| SCHEMBL7428797 | 0.74 | CPN1 (0.38) | CPN1CPB2SLC6A1SLC6A11TSHR | |
| SCHEMBL4769110 | 0.73 | CPB2 (0.42) | CPN1CPB2 | |
| SCHEMBL4769116 | 0.73 | CPB2 (0.42) | CPN1CPB2 | |
| SCHEMBL6206698 | 0.73 | KDM4E (0.38) | CPN1CPB2SLC6A1SLC6A11TSHR | |
| SCHEMBL4762118 | 0.70 | SLC6A2 (0.36) | LMNA | |
| SCHEMBL5983633 | 0.69 | CPB2 (0.39) | CPN1CPB2SLC6A1SLC6A11TSHR | |
| SCHEMBL3956504 | 0.69 | CTSK (0.40) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320370-A4 | METHOD OF TREATMENT | SMITHKLINE BEECHAM CORP (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1320370-A1 | METHOD OF TREATMENT | SmithKline Beecham Corporation (US) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002017924-A1 | METHOD OF TREATMENT | SMITHKLINE BEECHAM CORPORATION (GB) | 2002-03-07 | — | — | WO | disclosed |