Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 8/20 | 0.34 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 2/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.31 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763418 | 1.00 | ADORA2A (0.39) | ADORA2AADORA2BADORA1ALDH1A1MAPK1 | |
| SCHEMBL4771574 | 0.93 | ADORA2A (0.39) | ADORA2AADORA2BADORA1ALDH1A1MAPK1 | |
| SCHEMBL4771562 | 0.93 | ADORA2A (0.39) | ADORA2AADORA2BADORA1ALDH1A1MAPK1 | |
| SCHEMBL4763642 | 0.93 | ADORA2A (0.35) | ADORA2AADORA2BADORA1ALDH1A1MAPK1 | |
| SCHEMBL4763634 | 0.93 | ADORA2A (0.35) | ADORA2AADORA2BADORA1ALDH1A1MAPK1 | |
| SCHEMBL4762591 | 0.90 | MAPT (0.37) | ADORA2AADORA2BADORA1ALDH1A1SCD5 | |
| SCHEMBL4762596 | 0.90 | MAPT (0.37) | ADORA2AADORA2BADORA1ALDH1A1SCD5 | |
| SCHEMBL4769025 | 0.90 | C5AR1 (0.37) | ADORA2AADORA2BADORA1 | |
| SCHEMBL4769016 | 0.90 | C5AR1 (0.37) | ADORA2AADORA2BADORA1 | |
| SCHEMBL4762538 | 0.89 | NPBWR1 (0.44) | ADORA2AADORA2BADORA1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678181-B1 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS INC (US) | 2008-12-31 | — | — | EP | disclosed |