SCHEMBL476372

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL476489	0.99	MMP2 (0.37)	MMP2MMP9MMP8MMP13NFE2L2
	SCHEMBL476271	0.90	HTR6 (0.40)	POLBSMN1; SMN2
	Hydrochloric Acid SCHEMBL3690326	0.90	NFE2L2 (0.42)	NFE2L2LMNATSHRGLO1SLC40A1
	Hydrochloric Acid SCHEMBL476306	0.89	HTR6 (0.40)	POLBSMN1; SMN2
	SCHEMBL3695259	0.89	HTR6 (0.36)	NAMPT
	SCHEMBL476443	0.88	CA1 (0.45)	MMP2MMP9MMP8MMP13NFE2L2
	Hydrochloric Acid SCHEMBL3695929	0.88	HTR6 (0.36)	SLC40A1NAMPT
	SCHEMBL476445	0.83	HTR6 (0.38)	KMT2AMEN1SLC40A1NAMPTPKM
	Hydrochloric Acid SCHEMBL3703128	0.83	HTR6 (0.46)	NFE2L2
	Hydrochloric Acid SCHEMBL476331	0.82	HTR6 (0.38)	KMT2AMEN1SLC40A1NAMPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.