Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC5 | O15392 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MYLK | Q15746 | 1/20 | 0.31 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703057 | 0.85 | TACR1 (0.37) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL27703083 | 0.83 | PTGDR2 (0.38) | ALDH1A1LMNAHPGD | |
| SCHEMBL4608351 | 0.82 | AQP1 (0.42) | — | |
| SCHEMBL27703084 | 0.80 | GAA (0.41) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL5583525 | 0.79 | S1PR4 (0.34) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL4960255 | 0.77 | CETP (0.35) | — | |
| SCHEMBL4597042 | 0.76 | AQP1 (0.39) | BIRC5PDE2AALDH1A1KDM1A | |
| SCHEMBL4770057 | 0.76 | S1PR4 (0.37) | PDE2AALDH1A1P2RX1MEN1KMT2A | |
| SCHEMBL27703072 | 0.76 | TDP2 (0.38) | ALDH1A1 | |
| SCHEMBL4597043 | 0.75 | AQP1 (0.38) | BIRC5PDE2AALDH1A1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871356-A1 | DIHYDROBENZOFURAN DERIVATIVES AND USES THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006116170-A1 | DIHYDROBENZOFURAN DERIVATIVES AND USES THEREOF | WYETH (US) | 2006-11-02 | — | — | WO | disclosed |