Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596068 | 0.88 | F2RL3 (0.38) | MAPTMAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL27723655 | 0.84 | PLA2G7 (0.37) | ALDH1A1HPGDKMT2ATP53 | |
| SCHEMBL4608351 | 0.82 | AQP1 (0.42) | MAPTMAPK1NPSR1TDP1L3MBTL1 | |
| SCHEMBL27723629 | 0.82 | AHR (0.33) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL4770057 | 0.82 | S1PR4 (0.37) | S1PR4MAPTMAPK1NPSR1TDP1 | |
| SCHEMBL4763783 | 0.79 | BIRC5 (0.35) | ALDH1A1LMNAMEN1HPGDKMT2A | |
| SCHEMBL27723634 | 0.78 | HTR1A (0.38) | ALDH1A1 | |
| SCHEMBL4596615 | 0.77 | AQP1 (0.39) | MAPTNPSR1TDP1KDM4EALDH1A1 | |
| SCHEMBL4766477 | 0.74 | AQP1 (0.39) | S1PR4MAPTMAPK1NPSR1TDP1 | |
| SCHEMBL4766472 | 0.73 | AQP1 (0.38) | S1PR4MAPTMAPK1NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007509174-A | — | — | 2007-04-12 | — | — | JP | claimed |
| EP-1675840-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2006-07-05 | — | — | EP | claimed |
| WO-2005044812-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH A CORPORATION OF THE STATE OF DELAWARE (US) | 2005-05-19 | — | — | WO | claimed |