SCHEMBL476397

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3691249	0.91	CA9 (0.46)	CHRNA7CA9MAPTSMN1; SMN2NPC1
	SCHEMBL476334	0.91	CHRNA7 (0.39)	CHRNA7ELANECA9MAPTNPC1
	SCHEMBL3694089	0.90	NFE2L2 (0.41)	CHRNA7ELANECA9MAPTTHRB
	SCHEMBL476450	0.89	CHRNA7 (0.50)	CHRNA7CA9THRBTP53KMT2A
	SCHEMBL476502	0.86	TP53 (0.45)	CHRNA7CA9SMN1; SMN2HPGDTP53
	SCHEMBL476363	0.81	HTR6 (0.39)	CA9KMT2AMEN1ALDH1A1PKM
	SCHEMBL3707095	0.80	CA9 (0.46)	CHRNA7CA9MAPTTHRBTP53
	SCHEMBL3698618	0.79	TP53 (0.52)	CHRNA7CA9MAPTSMN1; SMN2NPC1
	SCHEMBL476470	0.79	HTR6 (0.36)	ELANEKMT2AMEN1ALDH1A1GAA
	SCHEMBL476340	0.78	TP53 (0.45)	CHRNA7MAPTTHRBHPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.