Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.36 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4770044 | 0.85 | ALDH1A1 (0.39) | GPR119ALDH1A1CHRM3LMNAUCHL1 | |
| SCHEMBL4763365 | 0.80 | CHRM3 (0.42) | ALDH1A1CHRM3 | |
| SCHEMBL4764264 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CHRM3KDM4ELMNAMALT1 | |
| SCHEMBL4791257 | 0.77 | ALDH1A1 (0.38) | ALDH1A1CHRM3 | |
| SCHEMBL330988 | 0.76 | ALDH1A1 (0.49) | ALDH1A1LMNAMALT1 | |
| SCHEMBL330987 | 0.76 | ALDH1A1 (0.49) | ALDH1A1LMNAMALT1 | |
| SCHEMBL4792050 | 0.74 | CHRM3 (0.42) | ALDH1A1CHRM3 | |
| SCHEMBL4764117 | 0.74 | GPR119 (0.44) | GPR119CHRM3 | |
| SCHEMBL28505081 | 0.74 | POLB (0.47) | GPR119ALDH1A1KDM4ELMNA | |
| SCHEMBL28505082 | 0.74 | POLB (0.47) | GPR119ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881975-A1 | N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS USEFUL AS MONOAMINES REUPTAKE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006121218-A1 | N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS USEFUL AS MONOAMINES REUPTAKE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-11-16 | — | — | WO | disclosed |