Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330987 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNATSHRMALT1USP30 | |
| SCHEMBL330988 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNATSHRMALT1USP30 | |
| SCHEMBL4792050 | 0.78 | CHRM3 (0.42) | ALDH1A1CHRM3USP30 | |
| SCHEMBL4764117 | 0.78 | GPR119 (0.44) | CHRM3 | |
| SCHEMBL4764170 | 0.77 | RORC (0.40) | ALDH1A1CHRM3LMNAKDM4EMALT1 | |
| SCHEMBL28505081 | 0.77 | POLB (0.47) | ALDH1A1POLBLMNATSHRKDM4E | |
| SCHEMBL28505082 | 0.77 | POLB (0.47) | ALDH1A1POLBLMNATSHRKDM4E | |
| SCHEMBL4763365 | 0.77 | CHRM3 (0.42) | ALDH1A1CHRM3 | |
| SCHEMBL4762742 | 0.77 | CHRM3 (0.42) | ALDH1A1CHRM3LMNAUSP30NPSR1 | |
| SCHEMBL4766572 | 0.76 | CHRM3 (0.44) | ALDH1A1CHRM3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881975-A1 | N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS USEFUL AS MONOAMINES REUPTAKE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006121218-A1 | N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS USEFUL AS MONOAMINES REUPTAKE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-11-16 | — | — | WO | disclosed |