Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30046969 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAHTTTDP1NFE2L2 | |
| SCHEMBL10354553 | 0.82 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAHTTTDP1NFE2L2 | |
| SCHEMBL11400822 | 0.82 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAHTTTDP1NFE2L2 | |
| SCHEMBL29388965 | 0.79 | RPS6KA5 (0.45) | SMN1; SMN2LMNANFE2L2 | |
| SCHEMBL120643 | 0.79 | RPS6KA5 (0.45) | SMN1; SMN2LMNANFE2L2 | |
| SCHEMBL802211 | 0.79 | LMNA (0.41) | SMN1; SMN2LMNAHTTTDP1NFE2L2 | |
| Hydrochloric Acid SCHEMBL30667166 | 0.77 | RPS6KA5 (0.44) | SMN1; SMN2LMNATDP1NFE2L2ALDH1A1 | |
| SCHEMBL10354989 | 0.76 | KDM4E (0.32) | SMN1; SMN2LMNAHTTTDP1GAA | |
| SCHEMBL4679589 | 0.76 | LMNA (0.38) | SMN1; SMN2LMNATDP1NFE2L2GAA | |
| SCHEMBL30137376 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAHTTTDP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306658-B | Preparation method of chloropyridine and derivative thereof | 内蒙古中辉生物科技有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119592966-A | Method for synthesizing ester compounds by high-selectivity dechlorination electro-catalysis | 浙江工业大学 | 2025-03-11 | — | — | CN | claimed |
| CN-114292227-B | Method for preparing 2-chloro-3-trifluoromethyl pyridine | 大连九信精细化工有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-113429757-B | Biodegradable anti-fogging master batch for mulching film and preservative film | 东莞市金富亮塑胶科技有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-114292227-A | Method for preparing 2-chloro-3-trifluoromethylpyridine | 大连九信精细化工有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-113429757-A | Biodegradable anti-fogging master batch for mulching film and preservative film | 东莞市金富亮塑胶科技有限公司 | 2021-09-24 | — | — | CN | claimed |
| US-10815198-B2 | Method for separating and purifying 2-chloro-3-trifluoromethylpyridine | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2020-10-27 | — | — | US | claimed |
| CN-111004172-A | Preparation method and synthesis device of 2-chloro-3-trifluoromethylpyridine | 内蒙古元正精细化工有限责任公司 | 2020-04-14 | — | — | CN | claimed |
| US-20200048202-A1 | METHOD FOR SEPARATING AND PURIFYING 2-CHLORO-3-TRIFLUOROMETHYLPYRIDINE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2020-02-13 | — | — | US | claimed |
| EP-3608310-A1 | METHOD FOR SEPARATING AND PURIFYING 2-CHLORO-3-TRIFLUOROMETHYLPYRIDINE | Ishihara Sangyo Kaisha, Ltd. (JP) | 2020-02-12 | — | — | EP | claimed |
| EP-0144323-A1 | PRODUCTION OF POLYCHLORINATED PYRIDINE MIXTURES BY LIQUID PHASE CHLORINATION OF BETA-PICOLINE OR BETA-PICOLINE HYDROCHLORIDE | KALAMA CHEMICAL, INC. (US) | 1985-06-19 | — | — | EP | claimed |
| EP-0139648-A1 | PRODUCTION OF POLYCHLORINATED PYRIDINE MIXTURES BY LIQUID PHASE CHLORINATION OF BETA-PICOLINE OR BETA-PICOLINE HYDROCHLORIDE | KALAMA CHEMICAL, INC. (US) | 1985-05-08 | — | — | EP | claimed |
| US-4504665-A | Process for producing chloronicotinic acid compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1985-03-12 | — | — | US | claimed |
| US-4483993-A | MULTISTAGE CHLORINATION | KALAMA CHEMICAL, INC. (US) | 1984-11-20 | — | — | US | claimed |
| WO-1984004095-A1 | PRODUCTION OF POLYCHLORINATED PYRIDINE MIXTURES BY LIQUID PHASE CHLORINATION OF BETA-PICOLINE OR BETA-PICOLINE HYDROCHLORIDE | KALAMA CHEMICAL INC (US) | 1984-10-25 | — | — | WO | claimed |
| WO-1984004094-A1 | PRODUCTION OF POLYCHLORINATED PYRIDINE MIXTURES BY LIQUID PHASE CHLORINATION OF BETA-PICOLINE OR BETA-PICOLINE HYDROCHLORIDE | KALAMA CHEMICAL INC (US) | 1984-10-25 | — | — | WO | claimed |
| EP-0009212-B1 | PROCESS FOR PRODUCING 2-CHLORO-5-TRICHLOROMETHYLPYRIDINE | ISHIHARA SANGYO KAISHA LTD. (JP) | 1984-02-08 | — | — | EP | claimed |
| EP-0092117-A1 | Process for producing chloronicotinic acid compounds | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-10-26 | — | — | EP | claimed |
| US-4266064-A | CATALYTIC FLUORINATION IN A VAPOR PHASE | ISHIHARA SANGYO KAISHA LTD. (JP) | 1981-05-05 | — | — | US | claimed |
| US-4205175-A | Chlorination process | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-05-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048202-A1 | METHOD FOR SEPARATING AND PURIFYING 2-CHLORO-3-TRIFLUOROMETHYLPYRIDINE | PFAS, CLK2, CLK4 | SMN1; SMN2 4081/4885LMNA 4109/4885HTT 2263/4885 |
| US-10815198-B2 | Method for separating and purifying 2-chloro-3-trifluoromethylpyridine | PFAS, CLK2, CLK4 | SMN1; SMN2 4081/4885LMNA 4109/4885HTT 2263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.