Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.44 |
| ▸ | MET | P08581 | 2/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | SMURF1 | Q9HCE7 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4764992 | 0.96 | TP53 (0.51) | TP53ALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL4771101 | 0.88 | HRH3 (0.44) | TP53GAASMN1; SMN2HTTHRH3 | |
| Trifluoroacetic Acid SCHEMBL4772218 | 0.85 | SLC2A1 (0.42) | TP53GAASMN1; SMN2HTTHRH3 | |
| SCHEMBL4773051 | 0.84 | MAPT (0.56) | TP53ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL4774462 | 0.83 | RAB9A (0.59) | SMN1; SMN2KMT2AMEN1NPC1NFKB1 | |
| SCHEMBL4765254 | 0.83 | AXL (0.43) | TP53L3MBTL1GAASMN1; SMN2HTT | |
| SCHEMBL4777120 | 0.82 | NPY5R (0.54) | TP53SMN1; SMN2MAPTHRH3MET | |
| SCHEMBL4768161 | 0.82 | POLB (0.56) | TP53ALDH1A1LMNAKDM4EGAA | |
| SCHEMBL4768299 | 0.82 | KMT2A (0.59) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL4765564 | 0.82 | HRH3 (0.46) | TP53KDM4EGAASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |