Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | F10 | P00742 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4775487 | 0.95 | KMT2A (0.53) | KMT2ATSHRF10ALDH1A1LMNA | |
| SCHEMBL4767967 | 0.85 | HRH3 (0.48) | KMT2AALDH1A1LMNAHRH3MEN1 | |
| SCHEMBL4773051 | 0.85 | MAPT (0.56) | KMT2AALDH1A1LMNAHPGDHRH3 | |
| SCHEMBL4777120 | 0.85 | NPY5R (0.54) | HRH3 | |
| SCHEMBL4765564 | 0.85 | HRH3 (0.46) | KMT2AKDM4EHRH3MEN1 | |
| SCHEMBL4768724 | 0.83 | BLM (0.46) | KMT2AALDH1A1SMYD3HRH3MEN1 | |
| SCHEMBL4774462 | 0.82 | RAB9A (0.59) | KMT2AHPGDMEN1 | |
| SCHEMBL4765386 | 0.82 | TP53 (0.55) | KMT2AALDH1A1LMNAKDM4EHRH3 | |
| SCHEMBL4768161 | 0.81 | POLB (0.56) | KMT2AALDH1A1LMNAKDM4EHRH3 | |
| Trifluoroacetic Acid SCHEMBL4774586 | 0.81 | MAPT (0.51) | KMT2AALDH1A1LMNAHPGDHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |