SCHEMBL476551

SCHEMBL476551

Clc1cc(Cl)c(-c2nc(-c3ccccc3)c(-c3ccccc3)n2C2(c3c(Cl)cc(Cl)cc3Cl)N=C(c3ccccc3)C(c3ccccc3)=N2)c(Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.38
MGAM O43451 2/20 0.38
SI P14410 2/20 0.38
MGAM2 Q2M2H8 2/20 0.38
AKT1 P31749 5/20 0.35
AKT2 P31751 5/20 0.35
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
MDM2 Q00987 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3172557 0.90 AKT1 (0.38) GAAMGAMSIMGAM2AKT1
SCHEMBL1869206 0.84 MGAM (0.35) GAAMGAMSIMGAM2AKT1
SCHEMBL1872047 0.81 MGAM (0.40) GAAMGAMSIMGAM2AKT1
SCHEMBL1061886 0.80 MAPT (0.43) GAAAKT1AKT2KDM4E
SCHEMBL16746558 0.79 AKT1 (0.36) GAAAKT1AKT2KDM4E
SCHEMBL6693283 0.79 GAA (0.33) GAAMGAMSIMGAM2AKT1
SCHEMBL1868436 0.79 FABP4 (0.33) GAAMGAMSIMGAM2AKT1
SCHEMBL1864926 0.79 AKT1 (0.35) GAAMGAMSIMGAM2AKT1
SCHEMBL31734206 0.78 MGAM (0.41) GAAMGAMSIMGAM2AKT1
SCHEMBL1060924 0.78 MGAM (0.36) GAAMGAMSIMGAM2AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7932300-B2 Energy beam curable type ink jet printing ink JSR CORPORATION (JP) 2011-04-26 US claimed
US-6120973-A PHOTOSENSITIVE COMPOSITION AND COLORS WITH POLYMERS JSR CORPORATION (JP) 2000-09-19 US claimed
US-6087050-A Radiation sensitive composition and color filter JSR CORPORATION (JP) 2000-07-11 US claimed
EP-0902327-A2 Radiation sensitive composition JSR Corporation (JP) 1999-03-17 EP claimed
EP-0881541-A1 Radiation sensitive composition and color filter JSR Corporation (JP) 1998-12-02 EP claimed
EP-0875788-A1 Radiation sensitive composition for color filters JSR Corporation (JP) 1998-11-04 EP claimed
WO-2026100662-A1 LIQUID CRYSTAL ALIGNING AGENT AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2026-05-15 WO disclosed
WO-2026100726-A1 DECORATIVE FILM, ELECTRONIC MEMBER, AND TOUCH PAD JSR株式会社 2026-05-15 WO disclosed
US-12577432-B2 Organosilicon compound, production method therefor, and curable composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-17 US disclosed
EP-4282653-B1 ORGANOSILICON COMPOUND, PRODUCTION METHOD THEREFOR, AND CURABLE COMPOSITION SHINETSU CHEMICAL CO (JP) 2026-02-25 EP disclosed
US-12522684-B2 Active-energy-ray-curable resin composition and cured product thereof NIPPON SHOKUBAI CO., LTD. (JP) 2026-01-13 US disclosed
EP-4159779-B1 ACTIVE-ENERGY-RAY-CURABLE RESIN COMPOSITION AND CURED PRODUCT THEREOF NIPPON CATALYTIC CHEM IND (JP) 2025-12-10 EP disclosed
WO-2025127098-A1 PHASE DIFFERENCE FILM COMPOSITION AND SINGLE-LAYER PHASE DIFFERENCE MATERIAL 日産化学株式会社 2025-06-19 WO disclosed
US-6087050-A Radiation sensitive composition and color filter JSR CORPORATION (JP) 2000-07-11 US disclosed
US-6013415-A Radiation sensitive composition JSR CORPORATION (JP) 2000-01-11 US disclosed
EP-0902327-A2 Radiation sensitive composition JSR Corporation (JP) 1999-03-17 EP disclosed
EP-0893737-A2 Radiation sensitive composition JSR Corporation (JP) 1999-01-27 EP disclosed
EP-0881541-A1 Radiation sensitive composition and color filter JSR Corporation (JP) 1998-12-02 EP disclosed
EP-0875788-A1 Radiation sensitive composition for color filters JSR Corporation (JP) 1998-11-04 EP disclosed
EP-0866367-A2 Radiation sensitive composition JSR Corporation (JP) 1998-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577432-B2 Organosilicon compound, production method therefor, and curable composition ASH2L, DOT1L, DNMT3L GAA 1531/4885MGAM 2341/4885SI 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.