Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.38 |
| ▸ | CDK1 | P06493 | 4/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.38 |
| ▸ | CDK9 | P50750 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.37 |
| ▸ | CDK2 | P24941 | 4/20 | 0.37 |
| ▸ | CDK7 | P50613 | 2/20 | 0.37 |
| ▸ | CCNH | P51946 | 2/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788506 | 0.85 | CSNK2A2 (0.45) | ROCK1ALOX5CA9CA1CA2 | |
| SCHEMBL2788502 | 0.85 | CSNK2A2 (0.45) | ROCK1ALOX5CA9CA1CA2 | |
| SCHEMBL4770645 | 0.82 | NEK2 (0.39) | CCNT1CDK9CDK2CCNE1 | |
| SCHEMBL4772646 | 0.79 | KMT2A (0.52) | CA9CA1CA2CA4KMT2A | |
| SCHEMBL4774422 | 0.78 | CYP2C9 (0.36) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL4768062 | 0.74 | DYRK3 (0.38) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL4776074 | 0.74 | NPC1 (0.35) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL4768194 | 0.73 | BACE1 (0.36) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL4776063 | 0.72 | NQO1 (0.43) | CCNT1CDK9FLT3CDK6SLC2A1 | |
| SCHEMBL4770530 | 0.71 | PDE10A (0.46) | MAPK1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567112-B1 | THIAZOLIDIN-4-ONES FOR INHIBITING hYAK3 PROTEINS | SMITHKLINE BEECHAM CORP (US) | 2008-10-15 | — | — | EP | claimed |