Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4770645 | 0.91 | NEK2 (0.39) | GLO1MAPTKDR | |
| SCHEMBL2788312 | 0.83 | PIK3CD (0.45) | KMT2AMAPTALDH1A1POLBMEN1 | |
| SCHEMBL2788315 | 0.83 | PIK3CD (0.45) | KMT2AMAPTALDH1A1POLBMEN1 | |
| SCHEMBL4765576 | 0.81 | CHKA (0.41) | MAPT | |
| SCHEMBL4765880 | 0.78 | ROCK1 (0.43) | KMT2AMEN1L3MBTL1 | |
| SCHEMBL4776063 | 0.77 | NQO1 (0.43) | MAPTALDH1A1GLAKDM4ERAB9A | |
| SCHEMBL2788317 | 0.76 | PIK3CD (0.43) | MAPTPOLBNPC1RAB9AKDR | |
| SCHEMBL2788319 | 0.76 | PIK3CD (0.43) | MAPTPOLBNPC1RAB9AKDR | |
| SCHEMBL4772646 | 0.75 | KMT2A (0.52) | KMT2A | |
| SCHEMBL4768194 | 0.72 | BACE1 (0.36) | GLO1KMT2AHTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567112-B1 | THIAZOLIDIN-4-ONES FOR INHIBITING hYAK3 PROTEINS | SMITHKLINE BEECHAM CORP (US) | 2008-10-15 | — | — | EP | claimed |