Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4765216 | 0.94 | SLC2A1 (0.40) | RAB9ANPC1LMNAMAPTNFKB1 | |
| SCHEMBL4768724 | 0.84 | BLM (0.46) | RAB9ANPC1MAPTNFKB1NFKB2 | |
| Trifluoroacetic Acid SCHEMBL4774899 | 0.79 | SLC2A1 (0.43) | RAB9ANPC1MAPTNFKB1NFKB2 | |
| SCHEMBL1898414 | 0.78 | MAPT (0.50) | RAB9ANPC1MAPTKDM4EL3MBTL1 | |
| SCHEMBL1900139 | 0.77 | POLB (0.53) | RAB9ANPC1LMNAMAPTKDM4E | |
| SCHEMBL4776972 | 0.77 | AURKA (0.54) | RAB9ANPC1MAPTNFKB1NFKB2 | |
| SCHEMBL1789786 | 0.74 | HRH3 (0.42) | NPC1LMNAHRH3ALDH1A1HPGD | |
| SCHEMBL4777073 | 0.73 | POLB (0.52) | RAB9ANPC1HRH3GAAL3MBTL3 | |
| SCHEMBL4767967 | 0.73 | HRH3 (0.48) | RAB9ANPC1LMNAMAPTNFKB1 | |
| SCHEMBL4774439 | 0.72 | RAB9A (0.49) | RAB9ANPC1LMNAMAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |