Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898414 | 0.90 | MAPT (0.50) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28123456 | 0.79 | MAPT (0.61) | KDM4EALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL3064335 | 0.79 | L3MBTL1 (0.56) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL28838815 | 0.78 | HDAC6 (0.58) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL4765993 | 0.77 | RAB9A (0.42) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL1898402 | 0.75 | SMN1; SMN2 (0.52) | KDM4EALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL7744999 | 0.75 | TASP1 (0.55) | KDM4EALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL1899260 | 0.74 | ALDH1A1 (0.54) | POLBKDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL4818615 | 0.73 | MAPK14 (0.66) | — | |
| Trifluoroacetic Acid SCHEMBL4765216 | 0.73 | SLC2A1 (0.40) | KDM4EALDH1A1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252156-B1 | BLOCKADE OF VOLTAGE DEPENDENT SODIUM CHANNELS | UCL BUSINESS PLC (GB) | 2011-05-04 | — | — | EP | disclosed |