SCHEMBL4767007

SCHEMBL4767007

Cc1nc(Oc2ccccc2)c(N)c(N)c1CCOCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
L3MBTL1 Q9Y468 3/20 0.36
TDP1 Q9NUW8 1/20 0.36
ATP4A P20648 2/20 0.34
ATP4B P51164 2/20 0.34
TSHR P16473 1/20 0.34
LMNA P02545 1/20 0.34
HTT P42858 1/20 0.34
NAAA Q02083 1/20 0.34
KLKB1 P03952 1/20 0.33
MBOAT4 Q96T53 1/20 0.33
POLB P06746 1/20 0.33
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4775196 0.89 ALDH1A1 (0.44) ALDH1A1L3MBTL1TDP1ATP4AATP4B
SCHEMBL4777348 0.76 GBA1 (0.36) ALDH1A1L3MBTL1TDP1ATP4AATP4B
SCHEMBL6218252 0.75 HTT (0.38) ALDH1A1L3MBTL1LMNAHTTKLKB1
SCHEMBL6713344 0.71 CYP2C19 (0.42) ALDH1A1TSHRLMNAHTTSMN1; SMN2
SCHEMBL4775733 0.71 FES (0.35) ALDH1A1ATP4AATP4BLMNAHTT
SCHEMBL27634278 0.69 ALDH1A1 (0.51) ALDH1A1L3MBTL1TDP1TSHRHTT
SCHEMBL4765503 0.67 ALDH1A1 (0.46) ALDH1A1L3MBTL1TDP1TSHRLMNA
SCHEMBL26037955 0.65 TSHR (0.52) L3MBTL1ATP4AATP4BTSHRHTT
SCHEMBL16828235 0.64 ADORA2A (0.55) ALDH1A1TSHRLMNAHTTPOLB
SCHEMBL1066576 0.64 TSHR (0.67) ALDH1A1L3MBTL1TDP1TSHRNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1513524-A4 ETHER SUBSTITUTED IMIDAZOPYRIDINES 3M INNOVATIVE PROPERTIES CO (US) 2008-09-03 EP disclosed
US-7220758-B2 Ether substituted imidazopyridines 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-05-22 US disclosed
US-20060252792-A1 ETHER SUBSTITUTED IMIDAZOPYRIDINES 3M INNOVATIVE PROPERTIES COMPANY 2006-11-09 US disclosed
US-7125890-B2 Ether substituted imidazopyridines 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-10-24 US disclosed
EP-1513524-A2 ETHER SUBSTITUTED IMIDAZOPYRIDINES 3M Innovative Properties Company (US) 2005-03-16 EP disclosed
US-20050032830-A1 Immunology for viral diseases and biosynthesis of cytokines of anticancer drugs for tumors 3M INNOVATIVE PROPERTIES COMPANY 2005-02-10 US disclosed
US-6797718-B2 Ether substituted imidazopyridines 3M INNOVATIVE PROPERTIES COMPANY 2004-09-28 US disclosed
US-20040010007-A1 Ether substituted imidazopyridines 3M INNOVATIVE PROPERTIES COMPANY 2004-01-15 US disclosed
WO-2003103584-A2 ETHER SUBSTITUTED IMIDAZOPYRIDINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252792-A1 ETHER SUBSTITUTED IMIDAZOPYRIDINES IL2, IL4, MYD88 ALDH1A1 1803/4885L3MBTL1 2072/4885TDP1 2306/4885
US-20050032830-A1 Immunology for viral diseases and biosynthesis of cytokines of anticancer drugs for tumors IL2, IFNG, TSLP ALDH1A1 940/4885L3MBTL1 2518/4885TDP1 2716/4885
US-20040010007-A1 Ether substituted imidazopyridines IL2, IL4, MYD88 ALDH1A1 1803/4885L3MBTL1 2072/4885TDP1 2306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.