SCHEMBL26693286

SCHEMBL26693286

Fc1c(Cl)[nH]c2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
GPR3 P46089 2/20 0.50
HSD17B10 Q99714 2/20 0.50
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
RAB9A P51151 2/20 0.45
NR4A2 P43354 1/20 0.44
KDM4E B2RXH2 5/20 0.43
GAA P10253 3/20 0.43
AHR P35869 2/20 0.43
LMNA P02545 2/20 0.43
GLA P06280 2/20 0.43
HTT P42858 2/20 0.43
HPGD P15428 1/20 0.43
ATM Q13315 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PARP1 P09874 2/20 0.40
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
GABRA1 P14867 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1021516 0.76 ALDH1A1 (0.55) ALDH1A1GPR3HSD17B10KMT2AMEN1
SCHEMBL476707 0.75 KDM4E (0.53) ALDH1A1GPR3HSD17B10KMT2AMEN1
SCHEMBL4600671 0.74 ALDH1A1 (0.52) ALDH1A1GPR3HSD17B10KMT2AMEN1
SCHEMBL30981725 0.74 ALDH1A1 (0.52) ALDH1A1GPR3HSD17B10KMT2AMEN1
SCHEMBL31053100 0.74 TLR9 (0.46) ALDH1A1GPR3HSD17B10KMT2AMEN1
SCHEMBL30783368 0.73 AHR (0.61) ALDH1A1GPR3HSD17B10KMT2AMEN1
SCHEMBL28576393 0.73 ALDH1A1 (0.50) ALDH1A1GPR3HSD17B10KMT2AMEN1
SCHEMBL12813178 0.73 AHR (0.61) ALDH1A1GPR3HSD17B10KMT2AMEN1
SCHEMBL8083535 0.73 ALDH1A1 (0.50) ALDH1A1GPR3HSD17B10KMT2AMEN1
SCHEMBL6817362 0.73 AHR (0.61) ALDH1A1GPR3HSD17B10KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250354108-A1 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS UNIV DANMARKS TEKNISKE (DK) 2025-11-20 US disclosed
EP-4526426-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS Danmarks Tekniske Universitet (DK) 2025-03-26 EP disclosed
WO-2023222879-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS DANMARKS TEKNISKE UNIVERSITET (DK) 2023-11-23 WO disclosed
CN-103214414-B The diamine derivative of opticity and manufacture method thereof SANKYO CO. (JP) 2016-02-17 CN disclosed
CN-103214414-A Optically active diamine derivative and process for producing the same DAIICHI SANKYO CO LTD 2013-07-24 CN disclosed
CN-101263110-B Optically active diamine derivative and process for producing the same DAIICHI SANKYO CO LTD 2013-04-03 CN disclosed
CN-1751025-B Diamine derivatives DAIICHI SEIYAKU CO 2010-05-12 CN disclosed
CN-101263110-A Optically active diamine derivative and process for producing the same DAIICHI SANKYO CO LTD (JP) 2008-09-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250354108-A1 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS INMT, KARS1, MIA3 ALDH1A1 781/4885GPR3 1442/4885HSD17B10 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.