Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PCK1 | P35558 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762383 | 0.92 | MAPT (0.42) | MAPTALDH1A1MAPK1SMN1; SMN2TP53 | |
| SCHEMBL4767816 | 0.91 | MAPT (0.42) | MAPTALDH1A1MAPK1SMN1; SMN2TP53 | |
| SCHEMBL4767823 | 0.91 | MAPT (0.42) | MAPTALDH1A1MAPK1SMN1; SMN2TP53 | |
| SCHEMBL4762425 | 0.91 | ALDH1A1 (0.39) | MAPTALDH1A1MAPK1SMN1; SMN2POLB | |
| SCHEMBL4763451 | 0.91 | MAPT (0.52) | MAPTALDH1A1MAPK1SMN1; SMN2POLB | |
| SCHEMBL4763446 | 0.91 | MAPT (0.52) | MAPTALDH1A1MAPK1SMN1; SMN2POLB | |
| SCHEMBL4767860 | 0.90 | ALDH1A1 (0.40) | MAPTALDH1A1MAPK1SMN1; SMN2TP53 | |
| SCHEMBL4769234 | 0.88 | NPBWR1 (0.41) | MAPTALDH1A1MAPK1SMN1; SMN2TP53 | |
| SCHEMBL4794079 | 0.85 | MAPT (0.38) | MAPTALDH1A1MAPK1SMN1; SMN2TP53 | |
| SCHEMBL4794085 | 0.85 | MAPT (0.38) | MAPTALDH1A1MAPK1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678181-B1 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS INC (US) | 2008-12-31 | — | — | EP | disclosed |