Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | TRPM5 | Q9NZQ8 | 3/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21729966 | 0.74 | CSF1R (0.35) | ALDH1A1CSF1RFLT1RPS6KB1KDR | |
| SCHEMBL22969780 | 0.74 | NOS1 (0.39) | NOS1ALDH1A1CSF1RFLT1RPS6KB1 | |
| SCHEMBL658519 | 0.74 | NOS1 (0.39) | NOS1ALDH1A1CSF1RFLT1RPS6KB1 | |
| SCHEMBL11092129 | 0.74 | CSF1R (0.39) | LMNAALDH1A1TRPM5CSF1RFLT1 | |
| SCHEMBL12043521 | 0.74 | CYP1A2 (0.44) | CYP1A2CYP2A6ALDH1A1TRPM5CSF1R | |
| SCHEMBL911600 | 0.74 | KDM4E (0.39) | CYP1A2LMNAALDH1A1CSF1RFLT1 | |
| SCHEMBL8976268 | 0.74 | ALDH1A1 (0.44) | CYP1A2LMNAALDH1A1NR4A2CSF1R | |
| SCHEMBL26420 | 0.70 | TRPM5 (0.45) | CYP1A2CYP2A6NOS1LMNAPDE10A | |
| SCHEMBL21729955 | 0.69 | CSF1R (0.35) | ALDH1A1CSF1RFLT1RPS6KB1KDR | |
| SCHEMBL21026107 | 0.69 | CA2 (0.39) | ALDH1A1CSF1RFLT1RPS6KB1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411398-B1 | METHOD FOR MANUFACTURING A BORONIC ACID ESTER COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2014-12-17 | — | — | EP | disclosed |
| US-8785651-B2 | Method for manufacturing a boronic acid ester compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-07-22 | — | — | US | disclosed |
| US-20120123122-A1 | METHOD FOR MANUFACTURING A BORONIC ACID ESTER COMPOUND | GENENTECH, INC. (US) | 2012-05-17 | — | — | US | disclosed |
| EP-2411398-A1 | METHOD FOR MANUFACTURING A BORONIC ACID ESTER COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010110782-A1 | METHOD FOR MANUFACTURING A BORONIC ACID ESTER COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |
| EP-0454621-B1 | Nematicide agents | NOVARTIS AG (CH) | 2000-07-12 | — | — | EP | disclosed |
| US-5447945-A | Controlling or preventing nematocidal attack on cultivated plants with nitro- or halo-substituted benzisothiazoles | CIBA-GEIGY CORPORATION (US) | 1995-09-05 | — | — | US | disclosed |
| US-5169951-A | PROCESS FOR PREPARING NEMATICIDAL COMPOSITIONS | CIBA-GEIGY CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0454621-A2 | Nematicide agents | CIBA-GEIGY AG (CH) | 1991-10-30 | — | — | EP | disclosed |
| EP-0033984-B1 | NEW SULPHONYL COMPOUNDS, METHOD OF PREPARING THE NEW COMPOUNDS, AS WELL AS APHICIDAL COMPOSITIONS ON THE BASIS OF THE NEW COMPOUNDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-06-06 | — | — | EP | disclosed |
| EP-0039795-B1 | PROCESS FOR THE PREPARATION OF 1,2-BENZISOTHIAZOLES | BASF Aktiengesellschaft (DE) | 1983-10-12 | — | — | EP | disclosed |
| EP-0011188-B1 | PROCESS FOR PREPARING CYANOARYL ETHERS AND CYANOARYL THIOETHERS | BASF Aktiengesellschaft (DE) | 1982-04-28 | — | — | EP | disclosed |
| EP-0039795-A1 | Process for the preparation of 1,2-benzisothiazoles | BASF Aktiengesellschaft (DE) | 1981-11-18 | — | — | EP | disclosed |
| EP-0011188-A2 | Process for preparing cyanoaryl ethers and cyanoaryl thioethers | BASF Aktiengesellschaft (DE) | 1980-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123122-A1 | METHOD FOR MANUFACTURING A BORONIC ACID ESTER COMPOUND | NISCH, BRSK1, BLK | CYP1A2 2457/4885CYP2A6 732/4885NOS1 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.