Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 12/20 | 0.43 |
| ▸ | DRD4 | P21917 | 12/20 | 0.43 |
| ▸ | DRD3 | P35462 | 12/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4770554 | 0.87 | KDM4E (0.46) | KDM4EALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL4766169 | 0.86 | GAA (0.50) | KDM4EALDH1A1TP53HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL4765862 | 0.86 | KDM4E (0.45) | KDM4EALDH1A1TP53HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL4770410 | 0.85 | GAA (0.49) | KDM4EALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL4763611 | 0.85 | SMN1; SMN2 (0.43) | KDM4EALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL4766830 | 0.84 | MAPT (0.38) | ALDH1A1TP53HSD17B10PRMT5 | |
| Hydrochloric Acid SCHEMBL4766050 | 0.84 | SMN1; SMN2 (0.43) | KDM4EALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL4766232 | 0.83 | HTR7 (0.41) | ALDH1A1DRD2PRMT5 | |
| SCHEMBL4765280 | 0.83 | PRMT5 (0.44) | KDM4EALDH1A1HPGDPRMT5 | |
| SCHEMBL4771319 | 0.82 | SMN1; SMN2 (0.41) | KDM4EALDH1A1HPGDPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020445-B1 | FUSED PYRIDINE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-6875761-B2 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. (JP) | 2005-04-05 | — | — | US | disclosed |
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. | 2004-10-14 | — | — | US | disclosed |
| US-6790844-B2 | MUSCLE RELAXANTS; ANTISEROTONINE AGENT | EISAI CO., LTD (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20020013460-A1 | Condensed pyridine compound | EISAI CO., LTD | 2002-01-31 | — | — | US | disclosed |
| US-6340759-B1 | ANTISPASMODIC AGENTS | EISAI CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1020445-A1 | FUSED PYRIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013460-A1 | Condensed pyridine compound | MUSK, HTR1A, PAX3 | KDM4E 1050/4885ALDH1A1 2989/4885TP53 2427/4885 |
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | MUSK, HTR1A, RYR1 | KDM4E 1058/4885ALDH1A1 1071/4885TP53 3037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.