Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.89 |
| ▸ | CA4 | P22748 | 2/20 | 0.89 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 11/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL11789341 | 0.97 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL11422396 | 0.95 | CA2 (0.80) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL28337190 | 0.95 | CA2 (0.80) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL29624 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL4525348 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL1445056 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL12476955 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570059 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570232 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL579255 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 775 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12448536-B2 | Nano metal paste, and preparation and application thereof | GUANGDONG UNIVERSITY OF TECHNOLOGY (CN) | 2025-10-21 | — | — | US | claimed |
| US-20250297041-A1 | Polymer Composition Preparation Method and Polymer Composition | LG CHEM, LTD. (KR) | 2025-09-25 | — | — | US | claimed |
| EP-4571881-A1 | NEGATIVE ELECTRODE MATERIAL AND PREPARATION METHOD THEREFOR, AND BATTERY | BTR NEW MATERIAL GROUP CO., LTD. (CN) | 2025-06-18 | — | — | EP | claimed |
| CN-120054540-A | Residual oil hydrodenitrogenation catalyst, preparation method and application | 中国石油化工股份有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-120054541-A | Residual oil hydrogenation carbon residue removal catalyst, preparation method and application | 中国石油化工股份有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-120054539-A | Residual oil hydrodesulfurization catalyst, preparation method and application | 中国石油化工股份有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-120037919-A | Nickel-based catalyst and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-05-27 | — | — | CN | claimed |
| EP-4553092-A1 | POLYMER COMPOSITION PREPARATION METHOD AND POLYMER COMPOSITION | LG Chem, Ltd. (KR) | 2025-05-14 | — | — | EP | claimed |
| US-20250149567-A1 | ANODE MATERIAL, PREPARATION METHOD THEREOF, AND BATTERY | BTR NEW MATERIAL GROUP CO., LTD. (CN) | 2025-05-08 | — | — | US | claimed |
| CN-119841994-A | Polybutadiene, preparation method thereof and vulcanized rubber | 中国石油化工股份有限公司 | 2025-04-18 | — | — | CN | claimed |
| US-5237116-A | Grignard reagents, diphosphine complex with nickel sulfonate or carboxylate | SHELL OIL COMPANY (US) | 1993-08-17 | — | — | US | claimed |
| US-5053541-A | Condensation of allyamine with m-bromo-trifluoromethyl benzene in presence of nickel compound or complex as catalyst; catalyst selectivity | RHONE-POULENC CHIMIE (FR) | 1991-10-01 | — | — | US | claimed |
| US-4983695-A | Catalysis with nickel carboxylate, trialkylaluminum, and hydrogen fluoride ether complex | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-01-08 | — | — | US | claimed |
| US-4659644-A | Diazo-type thermosensitive recording material with hydrazone coupler and chelating metal compound | RICOH COMPANY, LTD. (JP) | 1987-04-21 | — | — | US | claimed |
| US-4539403-A | Process for the preparation of a 2-alkyl-4-amino-5-aminomethylpyrimidine | UBE INDUSTRIES, LTD. (JP) | 1985-09-03 | — | — | US | claimed |
| US-4471153-A | ADDING ORGANOALUMINUM, ZINC, OR MAGNESIUM COMPOUND, AN ORGANONICKEL COMPOUND | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-09-11 | — | — | US | claimed |
| US-4383097-A | USING NONCONJUGATED DIOLEFINS HAVING TRANS CONFIGURATION AND A CATALYST OF AN ORGANO ALUMINUM-NICKEL-FLUORINE COMPLEY | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-05-10 | — | — | US | claimed |
| US-4020118-A | CATALYTIC | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JA) | 1977-04-26 | — | — | US | claimed |
| US-3985941-A | MIXED FLUORIDE BEARING CATALYSTSOLUTION POLYMERIZATION OF BUTADIENE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-10-12 | — | — | US | claimed |
| US-3954708-A | Synthetic polymers stabilized with a nickel benzoate and a polyol | CIBA-GEIGY CORPORATION (US) | 1976-05-04 | — | — | US | claimed |