SCHEMBL476940

SCHEMBL476940

C=CC(=O)OCC[Si](C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.56
ALDH1A1 P00352 5/20 0.56
TP53 P04637 3/20 0.56
HIF1A Q16665 3/20 0.56
CYP3A4 P08684 2/20 0.56
HSD17B10 Q99714 1/20 0.56
HPGD P15428 1/20 0.55
THRB P10828 2/20 0.46
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ATM Q13315 1/20 0.34
HCAR2 Q8TDS4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL308812 0.88 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9637784 0.86 TSHR (0.67) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29467782 0.85 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
Ammonia Solution, Strong SCHEMBL28181274 0.84 TSHR (0.64) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7783389 0.83 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9805672 0.83 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7698331 0.83 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
Hydrochloric Acid SCHEMBL28821608 0.83 TSHR (0.62) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11030891 0.82 ATM (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL674051 0.82 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111883748-A Method for coating oxide film on surface of lithium ion battery anode powder material 华南理工大学 2020-11-03 CN claimed
CN-111883748-A Method for coating oxide film on surface of lithium ion battery anode powder material 华南理工大学 2020-11-03 CN disclosed
EP-3186226-B1 OXIME SULFONATE DERIVATIVES BASF SE (DE) 2020-06-17 EP disclosed
US-20190171099-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2019-06-06 US disclosed
US-10241399-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent BASF SE (DE) 2019-03-26 US disclosed
EP-2668156-B1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2018-10-31 EP disclosed
US-20170260132-A1 OXIME SULFONATE DERIVATIVES BASF SE (DE) 2017-09-14 US disclosed
EP-3186226-A1 OXIME SULFONATE DERIVATIVES BASF SE (DE) 2017-07-05 EP disclosed
US-9310677-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent BASF (DE) 2016-04-12 US disclosed
WO-2016030790-A1 OXIME SULFONATE DERIVATIVES BASF SE (DE) 2016-03-03 WO disclosed
WO-2007078819-A2 LOW SURFACE ENERGY BLOCK CO-POLYMER PREPARATION METHODS AND APPLICATIONS ARKEMA INC. (US) 2007-07-12 WO disclosed
US-20060128903-A1 Process for the controlled increase in the molecular weight of polyethylenes ROTH MICHAEL 2006-06-15 US disclosed
EP-1655303-A2 Hydroxylamine esters as polimerization initiators Ciba SC Holding AG (CH) 2006-05-10 EP disclosed
US-7030196-B2 Process for reducing the molecular weight of polypropylene CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-18 US disclosed
US-20030216494-A1 Hydroxylamine esters as polymerization initiators CIBA SPECIALTY CHEMICALS CORP. 2003-11-20 US disclosed
CN-1333790-A pigment composition containing ATRP polymers CIBA SPEICALTY CHEMICALS HOLDI (CH) 2002-01-30 CN disclosed
EP-0273457-B1 ANTIFOULING PAINT NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1992-07-08 EP disclosed
US-4898895-A Antifouling pain having a polyacrylate component with pendent silyl or siloxane groups NIPPON OIL AND FATS CO., LTD. (JP) 1990-02-06 US disclosed
US-4883852-A SILICON CONTAINING ACRYLIC ESTER POLYMER, POLYSILOXANES NIPPON OIL AND FATS CO., LTD. (JP) 1989-11-28 US disclosed
EP-0273457-A2 Antifouling paint NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10241399-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent SULT1E1, COX6B1, SULT1A1 TSHR 3974/4885ALDH1A1 776/4885TP53 4571/4885
US-20170260132-A1 OXIME SULFONATE DERIVATIVES CBR3, CBR1, C1R TSHR 132/4885ALDH1A1 1495/4885TP53 2732/4885
US-20030216494-A1 Hydroxylamine esters as polymerization initiators PNMT, HPGDS, HAAO TSHR 2473/4885ALDH1A1 941/4885TP53 3116/4885
US-20190171099-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT SULT1E1, COX6B1, SULT1A1 TSHR 3974/4885ALDH1A1 776/4885TP53 4571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.