Fluorene

Fluorene

SCHEMBL476957

C=CC(=O)OOOC(=O)C=C.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.44
MAOA P21397 2/20 0.42
MAPT P10636 3/20 0.41
CYP1A2 P05177 3/20 0.40
HTR2C P28335 2/20 0.40
HTR2B P41595 2/20 0.40
ADRA2A P08913 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
CYP3A4 P08684 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ADRA1D P25100 2/20 0.38
ADRA1A P35348 2/20 0.38
ADRA1B P35368 2/20 0.38
DRD2 P14416 1/20 0.38
HTR2A P28223 1/20 0.38
HTR7 P34969 1/20 0.38
RAB9A P51151 4/20 0.37
KDM4E B2RXH2 4/20 0.37
NPC1 O15118 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL2050161 0.92 SRD5A2 (0.42) SRD5A2MAOAMAPTCYP1A2HTR2C
Fluorene SCHEMBL28137058 0.83 RAB9A (0.47) SRD5A2MAOAMAPTCYP1A2HTR2C
Fluorene SCHEMBL1315275 0.81 SRD5A2 (0.46) SRD5A2MAOAMAPTCYP1A2HTR2C
Fluorene SCHEMBL29742590 0.80 SRD5A2 (0.55) SRD5A2MAOAMAPTCYP1A2HTR2C
Fluorene SCHEMBL31174575 0.80 SRD5A2 (0.55) SRD5A2MAOAMAPTCYP1A2HTR2C
Fluorene SCHEMBL29436955 0.80 SRD5A2 (0.55) SRD5A2MAOAMAPTCYP1A2HTR2C
Fluorene SCHEMBL1331342 0.80 SRD5A2 (0.55) SRD5A2MAOAMAPTCYP1A2HTR2C
Fluorene SCHEMBL28813138 0.78 SRD5A2 (0.53) SRD5A2MAOAMAPTCYP1A2HTR2C
Fluorene SCHEMBL27547758 0.76 RAB9A (0.42) SRD5A2MAOAMAPTCYP1A2HTR2C
Fluorene SCHEMBL27768970 0.76 HCAR2 (0.50) SRD5A2MAPTSLC6A2RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-05-11 US disclosed
CN-115210219-A Oxime ester photoinitiators 巴斯夫欧洲公司 2022-10-18 CN disclosed
US-20220121113-A1 OXIME ESTER PHOTOINITIATORS HAVING A SPECIAL AROYL CHROMOPHORE BASF SE (DE) 2022-04-21 US disclosed
EP-3044208-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2021-12-22 EP disclosed
EP-3914965-A1 OXIME ESTER PHOTOINITIATORS HAVING A SPECIAL AROYL CHROMOPHORE BASF SE (DE) 2021-12-01 EP disclosed
CN-113316744-A Oxime ester photoinitiators with specific aroyl chromophores 巴斯夫欧洲公司 2021-08-27 CN disclosed
US-10793555-B2 Oxime ester photoinitiators BASF SE (DE) 2020-10-06 US disclosed
WO-2020152120-A1 OXIME ESTER PHOTOINITIATORS HAVING A SPECIAL AROYL CHROMOPHORE BASF SE (DE) 2020-07-30 WO disclosed
EP-3186226-B1 OXIME SULFONATE DERIVATIVES BASF SE (DE) 2020-06-17 EP disclosed
US-20190171099-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2019-06-06 US disclosed
US-8507569-B2 Photoresist compositions BASF SE (DE) 2013-08-13 US disclosed
WO-2012101245-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2012-08-02 WO disclosed
US-20120038996-A1 PHOTORESIST COMPOSITIONS BASF SE (DE) 2012-02-16 US disclosed
EP-2411430-A1 PHOTORESIST COMPOSITION BASF SE (DE) 2012-02-01 EP disclosed
US-20110151379-A1 BLACK MATRIX COMPOSITION WITH HIGH LIGHT-SHIELDING AND IMPROVED ADHESION PROPERTIES LG CHEM, LTD. (KR) 2011-06-23 US disclosed
WO-2010108835-A1 PHOTORESIST COMPOSITION BASF SE (DE) 2010-09-30 WO disclosed
US-20050173809-A1 Wafer-level package and method for production thereof NIPPON STEEL CHEMICAL CO., LTD. (JP) 2005-08-11 US disclosed
EP-0598552-B1 Cross-linkable polymeric composition SOLA INT HOLDINGS (AU) 1999-06-02 EP disclosed
US-5502139-A ACRYLIC ESTERS CONTAINING FLUORENE RINGS, POLYOXYALKYLENE GLYCOL DIACRYLATE OR DIMETHACRYLATE, SULFUR MONOMER, LENSES, VIDEO DISKS SOLA INTERNATIONAL HOLDINGS LTD. (AU) 1996-03-26 US disclosed
EP-0598552-A2 Cross-linkable polymeric composition SOLA INTERNATIONAL HOLDINGS, LTD. (AU) 1994-05-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120038996-A1 PHOTORESIST COMPOSITIONS HAAO, CBR3, AKR1B10 SRD5A2 670/4885MAOA 165/4885MAPT 2903/4885
US-10793555-B2 Oxime ester photoinitiators NR2E3, OXER1, CBR3 SRD5A2 33/4885MAOA 626/4885MAPT 4764/4885
US-20190171099-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT SULT1E1, COX6B1, SULT1A1 SRD5A2 300/4885MAOA 884/4885MAPT 4085/4885
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS OCIAD1, OCIAD2, OXER1 SRD5A2 276/4885MAOA 895/4885MAPT 579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.