Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.49 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4768631 | 0.98 | GAA (0.55) | GBA1GAATBK1CHEK2ACP1 | |
| SCHEMBL28160650 | 0.88 | GAA (0.63) | GAACHEK2PARP10PARP15PARP2 | |
| SCHEMBL6260511 | 0.85 | GBA1 (0.62) | GBA1GAATBK1SLC6A4 | |
| SCHEMBL28325439 | 0.84 | GAA (0.60) | GAACHEK2PARP10PARP15PARP2 | |
| SCHEMBL12735893 | 0.84 | MAOB (0.58) | GAACHEK2ACP1PARP10PARP15 | |
| SCHEMBL7454910 | 0.83 | GBA1 (0.56) | GBA1GAATBK1P2RX7SLC6A4 | |
| SCHEMBL8648753 | 0.83 | GBA1 (0.56) | GBA1TBK1SLC6A4MAOB | |
| SCHEMBL3139626 | 0.83 | GBA1 (0.56) | GBA1GAATBK1SLC6A4 | |
| Hydrochloric Acid SCHEMBL6153782 | 0.83 | GBA1 (0.61) | GBA1GAATBK1SLC6A4 | |
| Hydrochloric Acid SCHEMBL1532745 | 0.83 | MAOB (0.56) | GAACHEK2ACP1PARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079899-A | Application of pharmaceutical composition in preparation of medicines for preventing or treating diseases related to Sirttail 7 protein | — | 2026-05-26 | — | — | CN | disclosed |
| CN-116829542-A | Benzothiazole and benzimidazole derivatives, pharmaceutically acceptable salts, preparation method thereof and pharmaceutical composition containing same as active ingredient | 韩国化学研究院 | 2023-09-29 | — | — | CN | disclosed |
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7348324-B2 | Cyclic amine compounds as CCR5 antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-03-25 | — | — | US | disclosed |
| EP-1886994-A1 | Cyclic amine compounds as CCR5 antagonists | Takeda Pharmaceutical Company Limited (JP) | 2008-02-13 | — | — | EP | disclosed |
| US-7049441-B2 | Process for preparation of benzylpiperidine compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-05-23 | — | — | US | disclosed |
| EP-1219605-B1 | UREA COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-05-10 | — | — | EP | disclosed |
| US-20060094877-A1 | Process for preparation of benzylpiperidine compounds | MIKI SHOKYO | 2006-05-04 | — | — | US | disclosed |
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| US-20050038257-A1 | Process for preparation of benzylpiperidine compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-02-17 | — | — | US | disclosed |
| US-6787650-B1 | CCR5 ANTAGONISTIC ACTIVITY; SUCH AS N-(3-(4-BENZYL-1-PIPERIDINYL)PROPYL)-N'-4-CHLOROPHENYL)-N-PHENYLUREA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| CN-1494529-A | Process for preparing benzylpiperidine compounds | 武田药品工业株式会社 | 2004-05-05 | — | — | CN | disclosed |
| EP-1359145-A1 | PROCESS FOR PREPARATION OF BENZYLPIPERIDINE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2003-11-05 | — | — | EP | disclosed |
| US-20030114443-A1 | Cyclic amine compounds as CCR5 antagonists | TOBIRA THERAPEUTICS, INC. | 2003-06-19 | — | — | US | disclosed |
| US-6562978-B1 | N-(3-(4-(4-(Aminocarbonyl)benzyl)-1-piperidinyl)propyl)-N-(3, 4-dichlorophenyl)-1-(methylsulfonyl)-4-piperidinecarboxamide or a salt thereof for treatment of AIDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-05-13 | — | — | US | disclosed |
| CN-1390201-A | cyclic amine compounds as CCR5 antagonists | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-08 | — | — | CN | disclosed |
| EP-1220842-A1 | CYCLIC AMINE COMPOUNDS AS CCR5 ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-10 | — | — | EP | disclosed |
| EP-1219605-A1 | UREA COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001025200-A1 | CYCLIC AMINE COMPOUNDS AS CCR5 ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-12 | — | — | WO | disclosed |
| CN-1243505-A | Benzamidine derivatives | AJINOMOTO KK (JP) | 2000-02-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114443-A1 | Cyclic amine compounds as CCR5 antagonists | CCR5, CCR1, CCR3 | GBA1 2987/4885GAA 4215/4885TBK1 4119/4885 |
| US-20050038257-A1 | Process for preparation of benzylpiperidine compounds | SBDS, DRD4, HRH1 | GBA1 703/4885GAA 1844/4885TBK1 1973/4885 |
| US-20060094877-A1 | Process for preparation of benzylpiperidine compounds | SBDS, DRD4, HRH1 | GBA1 703/4885GAA 1844/4885TBK1 1973/4885 |
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | GBA1 847/4885GAA 2875/4885TBK1 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.