Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 5/20 | 0.45 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4765579 | 0.84 | GNRHR (0.44) | GNRHRDCTPP1ALDH1A1HPGDPOLB | |
| SCHEMBL4762644 | 0.81 | DCTPP1 (0.49) | GNRHRDCTPP1ALDH1A1HPGDPOLB | |
| SCHEMBL4762494 | 0.78 | DCTPP1 (0.47) | DCTPP1ALDH1A1HPGDPOLBLMNA | |
| SCHEMBL4771453 | 0.76 | ADORA3 (0.44) | GNRHRALDH1A1HPGDLMNAMAPT | |
| SCHEMBL4771274 | 0.76 | PDE5A (0.46) | GNRHRPDE5APDE4APDE4BPDE4C | |
| SCHEMBL4769060 | 0.74 | DCTPP1 (0.42) | GNRHRDCTPP1ALDH1A1HPGDLMNA | |
| SCHEMBL4765718 | 0.74 | PDE4D (0.46) | GNRHRPOLBLMNANPSR1KMT2A | |
| SCHEMBL4769379 | 0.74 | ALDH1A1 (0.42) | GNRHRALDH1A1POLBLMNAMAPT | |
| SCHEMBL4767817 | 0.73 | PARG (0.38) | GNRHRALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL4771460 | 0.72 | PARG (0.39) | GNRHRALDH1A1HPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678181-B1 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS INC (US) | 2008-12-31 | — | — | EP | disclosed |