Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 11/20 | 0.39 |
| ▸ | CNR2 | P34972 | 10/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2382190 | 0.84 | F2RL3 (0.46) | F2RL3CNR1CNR2GABRA1GABRG2 | |
| SCHEMBL4577625 | 0.80 | PTGDR2 (0.47) | F2RL3L3MBTL1KDM4ECXCR3SMN1; SMN2 | |
| SCHEMBL2385830 | 0.79 | F2RL3 (0.41) | F2RL3CNR1CNR2KDM4EAPAF1 | |
| SCHEMBL2385228 | 0.79 | PTGDR2 (0.42) | F2RL3CNR1CNR2GABRA1GABRG2 | |
| SCHEMBL2383728 | 0.78 | F2RL3 (0.40) | F2RL3CNR1CNR2GABRA1GABRG2 | |
| SCHEMBL2384363 | 0.77 | CXCR3 (0.39) | F2RL3MAPTCXCR3SMN1; SMN2 | |
| SCHEMBL1336873 | 0.75 | GABRA1 (0.42) | F2RL3CNR1CNR2GABRA1GABRG2 | |
| SCHEMBL2385324 | 0.74 | ALDH1A1 (0.47) | L3MBTL1KDM4EAPAF1MAPTPKM | |
| SCHEMBL1339573 | 0.73 | KDM4E (0.46) | CNR1CNR2GABRA1GABRG2GABRB3 | |
| SCHEMBL3572533 | 0.73 | GABRA1 (0.38) | F2RL3CNR1CNR2GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556382-B1 | 3-PHENYL SUBSTITUTED PYRIDOINDOLONE, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2008-05-28 | — | — | EP | disclosed |