Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | QDPR | P09417 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28094425 | 0.89 | MEN1 (0.52) | MEN1KMT2AQDPRPDE4BALDH1A1 | |
| SCHEMBL8535241 | 0.88 | PDE4B (0.50) | MEN1KMT2AQDPRPDE4BALDH1A1 | |
| SCHEMBL6815771 | 0.85 | MEN1 (0.45) | MEN1KMT2AQDPRPDE4BALDH1A1 | |
| SCHEMBL5515302 | 0.84 | PDE4B (0.53) | MEN1KMT2APDE4BALDH1A1HPGD | |
| SCHEMBL3812754 | 0.82 | DRD2 (0.41) | MEN1KMT2AQDPRALDH1A1HPGD | |
| SCHEMBL7029357 | 0.81 | QDPR (0.52) | MEN1KMT2AQDPRALDH1A1LMNA | |
| SCHEMBL4206124 | 0.81 | PDE4B (0.48) | MEN1KMT2APDE4B | |
| SCHEMBL7938441 | 0.81 | KDM4E (0.46) | ALDH1A1LMNAMAPT | |
| SCHEMBL1094926 | 0.81 | PTGDR2 (0.55) | MEN1KMT2ATRPC6 | |
| SCHEMBL2637185 | 0.80 | MEN1 (0.77) | MEN1KMT2AALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590326-A4 | SUBSTITUTED ALKYL AMIDO PIPERIDINES | LUNDBECK & CO AS H (DK) | 2008-04-30 | — | — | EP | disclosed |
| EP-1590326-A2 | SUBSTITUTED ALKYL AMIDO PIPERIDINES | H. Lundbeck A/S (DK) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004064764-A2 | SUBSTITUTED ALKYL AMIDO PIPERIDINES | H. LUNDBECK A/S (DK) | 2004-08-05 | — | — | WO | disclosed |