Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.75 |
| ▸ | ATM | Q13315 | 1/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.65 |
| ▸ | BRAF | P15056 | 1/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.62 |
| ▸ | AURKA | O14965 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681990 | 0.86 | L3MBTL1 (1.00) | LMNAL3MBTL1ATMTP53ALDH1A1 | |
| SCHEMBL28347241 | 0.84 | LMNA (0.73) | LMNAL3MBTL1ATMTP53ALDH1A1 | |
| SCHEMBL6677998 | 0.83 | LMNA (0.71) | LMNAL3MBTL1ATMTP53ALDH1A1 | |
| SCHEMBL22095074 | 0.83 | MAPT (0.80) | LMNATP53ALDH1A1HPGDKMT2A | |
| SCHEMBL6682820 | 0.82 | HPGD (1.00) | LMNAL3MBTL1ATMTP53ALDH1A1 | |
| SCHEMBL4501557 | 0.82 | ALDH1A1 (0.82) | LMNAL3MBTL1ATMTP53ALDH1A1 | |
| SCHEMBL6680213 | 0.82 | MEN1 (0.69) | LMNAL3MBTL1ATMTP53ALDH1A1 | |
| SCHEMBL22095109 | 0.81 | LMNA (0.67) | LMNATP53ALDH1A1HPGDKMT2A | |
| SCHEMBL28548195 | 0.80 | KMT2A (0.74) | LMNAL3MBTL1ATMTP53ALDH1A1 | |
| SCHEMBL28771391 | 0.80 | ALDH1A1 (0.78) | LMNAL3MBTL1ATMTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | disclosed |