Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.81 |
| ▸ | MEN1 | O00255 | 3/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.81 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | AURKA | O14965 | 7/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | CDK1 | P06493 | 1/20 | 0.65 |
| ▸ | CDK4 | P11802 | 1/20 | 0.65 |
| ▸ | CDK2 | P24941 | 1/20 | 0.65 |
| ▸ | CDK7 | P50613 | 1/20 | 0.65 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.65 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977618 | 0.88 | L3MBTL1 (0.79) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL23928576 | 0.87 | L3MBTL1 (0.77) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL4771997 | 0.86 | LMNA (1.00) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL28347215 | 0.86 | L3MBTL1 (0.75) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL28771391 | 0.86 | ALDH1A1 (0.78) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL4501557 | 0.85 | ALDH1A1 (0.82) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL30963700 | 0.85 | L3MBTL1 (0.74) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL6692762 | 0.85 | AURKA (1.00) | L3MBTL1ALDH1A1MEN1KMT2AAURKA | |
| SCHEMBL6683128 | 0.85 | L3MBTL1 (0.73) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL23928522 | 0.84 | MAPT (0.74) | L3MBTL1ATMALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |