SCHEMBL4772286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4769223	0.88	CYP1A2 (0.48)	RAB9ACYP1A2CYP3A4CYP2C9CYP2B6
	SCHEMBL4763954	0.88	NPC1 (0.58)	NPC1RAB9AKDM4EALDH1A1HPGD
	SCHEMBL4771340	0.79	KMT2A (0.61)	NPC1RAB9AKDM4EALDH1A1HPGD
	SCHEMBL28619679	0.79	CYP1A2 (0.44)	RAB9ACYP1A1CYP1B1CYP1A2CYP2A6
	SCHEMBL15618343	0.78	CASP3 (0.48)	CASP3SENP7NPC1RAB9ACYP1A1
	SCHEMBL31388225	0.78	MEN1 (0.55)	RAB9AKDM4EALDH1A1HPGDMEN1
	SCHEMBL786133	0.78	MEN1 (0.55)	RAB9AKDM4EALDH1A1HPGDMEN1
	SCHEMBL4771500	0.78	CCR1 (0.57)	NPC1RAB9ACYP1A2CYP3A4CYP2A6
	SCHEMBL4766668	0.77	KDM4E (0.58)	CASP3SENP7NPC1RAB9ACYP3A4
	SCHEMBL1536512	0.77	NPC1 (0.57)	CASP3SENP7NPC1RAB9ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.