Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 3/20 | 0.65 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.65 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.65 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.52 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136814 | 0.84 | AURKA (0.58) | RAB9ANPC1AURKAAURKBSMN1; SMN2 | |
| SCHEMBL29134257 | 0.81 | ALDH1A1 (0.56) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL29196087 | 0.81 | MAPK13 (0.95) | MAPK13MAPK12MAPK11MAPK14DHODH | |
| SCHEMBL609197 | 0.81 | BCL6 (0.57) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL5154269 | 0.79 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14DHODH | |
| SCHEMBL10382992 | 0.79 | RAB9A (0.44) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL28121626 | 0.79 | NPC1 (0.60) | TTBK1TTBK2MEN1KMT2ARAB9A | |
| SCHEMBL4774160 | 0.78 | BCL6 (0.46) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL2742816 | 0.77 | MAPK13 (0.95) | MAPK13MAPK12MAPK11MAPK14DHODH | |
| SCHEMBL11963751 | 0.77 | RHOA (0.67) | MEN1KMT2ARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891050-A1 | NEW DERIVATIVES OF PYRROLYLTRIAZINE TOGETHER WITH METHODS FOR OBTAINING THEM AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2008-02-27 | — | — | EP | claimed |
| WO-2006128920-A1 | NEW DERIVATIVES OF PYRROLYLTRIAZINE TOGETHER WITH METHODS FOR OBTAINING THEM AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2006-12-07 | — | — | WO | claimed |
| WO-2006128791-A1 | NEW DERIVATIVES OF PYRROLYLTRIAZINE TOGETHER WITH METHODS FOR OBTAINING THEM AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2006-12-07 | — | — | WO | claimed |
| EP-1891050-A1 | NEW DERIVATIVES OF PYRROLYLTRIAZINE TOGETHER WITH METHODS FOR OBTAINING THEM AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006128920-A1 | NEW DERIVATIVES OF PYRROLYLTRIAZINE TOGETHER WITH METHODS FOR OBTAINING THEM AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006128791-A1 | NEW DERIVATIVES OF PYRROLYLTRIAZINE TOGETHER WITH METHODS FOR OBTAINING THEM AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2006-12-07 | — | — | WO | disclosed |