SCHEMBL609197

SCHEMBL609197

c1ccc(Nc2ncncn2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL6 P41182 1/20 0.57
HSD17B10 Q99714 2/20 0.50
MAPT P10636 4/20 0.48
MAPK1 P28482 3/20 0.48
AURKA O14965 2/20 0.48
PDPK1 O15530 2/20 0.48
CDK1 P06493 2/20 0.48
LYN P07948 2/20 0.48
FGFR1 P11362 2/20 0.48
FGFR3 P22607 2/20 0.48
RPS6KB1 P23443 2/20 0.48
CDK2 P24941 2/20 0.48
MARK3 P27448 2/20 0.48
BLK P51451 2/20 0.48
RPS6KA3 P51812 2/20 0.48
ERBB4 Q15303 2/20 0.48
MARK2 Q7KZI7 2/20 0.48
PLK3 Q9H4B4 2/20 0.48
PRKCD Q05655 2/20 0.48
RAB9A P51151 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29134257 0.96 ALDH1A1 (0.56) BCL6HSD17B10MAPTMAPK1AURKA
SCHEMBL10382992 0.87 RAB9A (0.44) BCL6HSD17B10MAPTMAPK1AURKA
SCHEMBL4774160 0.87 BCL6 (0.46) BCL6HSD17B10MAPTMAPK1AURKA
SCHEMBL9325233 0.85 BCL6 (0.49) BCL6HSD17B10MAPTMAPK1AURKA
SCHEMBL8477006 0.82 ALDH1A1 (0.43) BCL6HSD17B10MAPTMAPK1RAB9A
SCHEMBL7520911 0.82 ALDH1A1 (0.43) BCL6HSD17B10MAPTMAPK1RAB9A
SCHEMBL4772313 0.81 MAPK13 (0.65) MAPTAURKARAB9ANPC1MEN1
SCHEMBL824411 0.81 BCL6 (0.74) BCL6HSD17B10MAPTMAPK1AURKA
Pyrimidine SCHEMBL27837500 0.80 MAPT (0.53) BCL6HSD17B10MAPTMAPK1AURKA
SCHEMBL15968669 0.80 AURKA (0.63) BCL6HSD17B10MAPTMAPK1AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430815-A Multi-chiral covalent organic framework chiral separation medium and preparation method and application thereof 中山大学 2024-01-23 CN claimed
US-20230040911-A1 Oil-In-Water-Type Emulsion Cosmetic L V M H RECHERCHE (FR) 2023-02-09 US claimed
EP-4076348-A1 OIL-IN-WATER-TYPE EMULSION COSMETIC L V M H RECHERCHE (FR) 2022-10-26 EP claimed
CN-115151236-A Oil-in-water type emulsion cosmetic LVMH研究公司 2022-10-04 CN claimed
WO-2021151452-A1 OIL-IN-WATER-TYPE EMULSION COSMETIC L V M H RECHERCHE (FR) 2021-08-05 WO claimed
CN-109096455-A A kind of preparation method and its rubber composition of modified alkyl phenolic tackifying resins 山东圣泉新材料股份有限公司 2018-12-28 CN claimed
CN-108410422-A A kind of preparation method of siliceous absorbing material 王金桢 2018-08-17 CN claimed
EP-2481730-B1 Insecticidal (1,3,5)-triazinyl phenyl hydrazones DOW AGROSCIENCES LLC (US) 2013-12-18 EP claimed
EP-2481731-B1 Insecticidal (1,3,5)-triazinyl phenyl hydrazones DOW AGROSCIENCES LLC (US) 2013-10-23 EP claimed
EP-2197857-B1 INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES DOW AGROSCIENCES LLC (US) 2013-03-06 EP claimed
EP-2197857-A2 INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES Dow AgroSciences LLC (US) 2010-06-23 EP claimed
WO-2009048750-A2 INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES DOW AGROSCIENCES LLC (US) 2009-04-16 WO claimed
US-20090093481-A1 INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES DOW AGROSCIENCES LLC (US) 2009-04-09 US claimed
CN-1273520-C Process for producing micro granular coloring resin, and coloring method for micro granular coloring resin DAINICHISEIKA COLOR CHEM (JP) 2006-09-06 CN claimed
EP-1132387-B1 PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES KUMIAI CHEMICAL INDUSTRY CO (JP) 2005-09-28 EP claimed
US-6576631-B1 Broad disease control spectrum; residual effectiveness, rainfastness; nondamaging to crops KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2003-06-10 US claimed
CN-1364822-A Process for producing micro granular coloring resin, and coloring method for micro granular coloring resin DAINICHISEIKA COLOR CHEM (JP) 2002-08-21 CN claimed
EP-1132387-A1 PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURA/HORTICULTURAL BACTERICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2001-09-12 EP claimed
CN-1295832-A Cosmetics Compositions having at least one kind of siloxanes/ester acrylate and at least one kind of photo protective agent OREAL (FR) 2001-05-23 CN claimed
EP-0039306-B1 AZO DYESTUFFS, METHODS FOR THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1984-01-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090093481-A1 INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES HELZ, API5, CRYZ BCL6 3463/4885HSD17B10 739/4885MAPT 2948/4885
US-20230040911-A1 Oil-In-Water-Type Emulsion Cosmetic CUTA, PHOSPHO1, LIPE BCL6 4563/4885HSD17B10 892/4885MAPT 862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.