Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK3 | O43781 | 4/20 | 0.69 |
| ▸ | GSK3B | P49841 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | NSD2 | O96028 | 1/20 | 0.58 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.57 |
| ▸ | GALR3 | O60755 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4772304 | 0.88 | DYRK3 (0.68) | DYRK3GSK3BMEN1POLBKMT2A | |
| SCHEMBL4765545 | 0.87 | DYRK3 (0.57) | DYRK3GSK3BMEN1POLBKMT2A | |
| SCHEMBL4770970 | 0.85 | DYRK3 (0.52) | DYRK3GSK3BMEN1POLBKMT2A | |
| SCHEMBL4771030 | 0.85 | DYRK3 (0.53) | DYRK3GSK3BMEN1POLBKMT2A | |
| SCHEMBL4770141 | 0.85 | MEN1 (0.56) | DYRK3MEN1POLBKMT2APTPN11 | |
| SCHEMBL4772146 | 0.85 | DYRK3 (0.54) | DYRK3GSK3BMEN1POLBKMT2A | |
| SCHEMBL4775509 | 0.85 | DYRK3 (0.55) | DYRK3GSK3BMEN1POLBKMT2A | |
| SCHEMBL4774341 | 0.84 | MAPT (0.64) | DYRK3MEN1POLBKMT2ANSD2 | |
| SCHEMBL4770725 | 0.83 | DYRK3 (0.51) | DYRK3GSK3BMEN1POLBKMT2A | |
| SCHEMBL2786117 | 0.82 | DYRK3 (1.00) | DYRK3GSK3BMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567112-B1 | THIAZOLIDIN-4-ONES FOR INHIBITING hYAK3 PROTEINS | SMITHKLINE BEECHAM CORP (US) | 2008-10-15 | — | — | EP | claimed |