SCHEMBL477347

SCHEMBL477347

CCC(C)CC(O)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.65
AOC3 Q16853 6/20 0.47
TRPA1 O75762 5/20 0.47
KDM4E B2RXH2 3/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
RIPK1 Q13546 1/20 0.46
ALDH1A1 P00352 1/20 0.42
ADRA2A P08913 1/20 0.42
ADRA2C P18825 1/20 0.42
HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5007837 0.83 LMNA (0.46) LMNAAOC3TRPA1KDM4ERIPK1
SCHEMBL13965237 0.82 LMNA (0.42) LMNAKDM4EALDH1A1HIF1A
SCHEMBL4957871 0.81 LMNA (0.68) LMNAAOC3TRPA1KDM4EL3MBTL1
SCHEMBL477603 0.81 LMNA (0.68) LMNAAOC3TRPA1KDM4EL3MBTL1
SCHEMBL3097213 0.80 LMNA (0.60) LMNAAOC3TRPA1KDM4EL3MBTL1
SCHEMBL477671 0.80 LMNA (0.60) LMNAAOC3TRPA1KDM4EL3MBTL1
SCHEMBL13433806 0.80 LMNA (0.60) LMNAAOC3TRPA1KDM4EL3MBTL1
SCHEMBL75953 0.80 LMNA (0.60) LMNAAOC3TRPA1KDM4EL3MBTL1
SCHEMBL13619949 0.80 LMNA (0.60) LMNAAOC3TRPA1KDM4EL3MBTL1
SCHEMBL13433805 0.80 LMNA (0.60) LMNAAOC3TRPA1KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110144139-B Zinc oxide-based nanoparticle ink and photoelectric device 纳晶科技股份有限公司 2022-01-18 CN claimed
US-20180265805-A1 RELEASE OF ODORIFEROUS SUBSTANCES FROM MICROCAPSULES HENKEL AG & CO. KGAA (DE) 2018-09-20 US claimed
EP-3350306-A1 RELEASE OF ODORIFEROUS SUBSTANCES FROM MICROCAPSULES Henkel AG & Co. KGaA (DE) 2018-07-25 EP claimed
US-9981937-B2 Orthoformic acid esters as pro-fragrances HENKEL AG & CO. KGAA (DE) 2018-05-29 US claimed
US-20170349565-A1 ORTHOFORMIC ACID ESTERS AS PRO-FRAGRANCES HENKEL AG & CO. KGAA (DE) 2017-12-07 US claimed
EP-3233821-A1 ORTHOFORMIC ACID ESTERS AS PRO-FRAGRANCES Henkel AG & Co. KGaA (DE) 2017-10-25 EP claimed
WO-2017045893-A1 RELEASE OF ODORIFEROUS SUBSTANCES FROM MICROCAPSULES HENKEL AG & CO. KGAA (DE) 2017-03-23 WO claimed
WO-2016096540-A1 ORTHOFORMIC ACID ESTERS AS PRO-FRAGRANCES HENKEL AG & CO. KGAA (DE) 2016-06-23 WO claimed
EP-1716159-B1 BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS MOMENTIVE PERFORMANCE MAT INC (US) 2011-07-13 EP claimed
US-7579495-B2 Active-releasing cyclic siloxanes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-08-25 US claimed
EP-1697386-B1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GEN ELECTRIC (US) 2007-10-10 EP claimed
US-20050136021-A1 Active-releasing cyclic siloxanes MOMENTIVE PERFORMANCE MATERIALS INC. 2005-06-23 US claimed
US-20050136022-A1 Cyclic siloxane compositions for the release of active ingredients MOMENTIVE PERFORMANCE MATERIALS INC. 2005-06-23 US claimed
EP-0009540-B1 FRAGRANCE COMPOSITIONS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1983-03-02 EP claimed
US-20250326984-A1 FRAGRANCES WITH CYCLOPROPYL STRUCTURE SYMRISE AG (DE) 2025-10-23 US disclosed
EP-4532455-A1 FRAGRANCES WITH CYCLOPROPYL STRUCTURE Symrise AG (DE) 2025-04-09 EP disclosed
CN-119255980-A Perfume with cyclopropyl structure 西姆莱斯股份公司 2025-01-03 CN disclosed
US-4210554-A DETERGENTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1980-07-01 US disclosed
US-4206090-A PERFUMES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1980-06-03 US disclosed
EP-0009540-A2 Fragrance compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1980-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250326984-A1 FRAGRANCES WITH CYCLOPROPYL STRUCTURE CBR3, CNR1, CBR1 LMNA 2784/4885AOC3 373/4885TRPA1 11/4885
US-20170349565-A1 ORTHOFORMIC ACID ESTERS AS PRO-FRAGRANCES FAAH, NISCH, ELOVL6 LMNA 1673/4885AOC3 282/4885TRPA1 5/4885
US-20050136022-A1 Cyclic siloxane compositions for the release of active ingredients F9, RPL39, ECPAS LMNA 568/4885AOC3 1528/4885TRPA1 469/4885
US-20050136021-A1 Active-releasing cyclic siloxanes F9, RPL39, ALDH16A1 LMNA 882/4885AOC3 1472/4885TRPA1 489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.