Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2088669 | 0.88 | CYP19A1 (0.49) | CYP19A1ALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL3119171 | 0.81 | CYP19A1 (0.53) | CYP19A1ALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL9933002 | 0.81 | CYP19A1 (0.53) | CYP19A1ALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL9819816 | 0.81 | HRH1 (0.59) | CYP19A1ALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL1610644 | 0.79 | MTNR1A (0.49) | CYP19A1ALDH1A1MTNR1AMTNR1BSLC6A2 | |
| SCHEMBL8101938 | 0.79 | CSNK1E (0.53) | CYP19A1ALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL9819796 | 0.79 | ALDH1A1 (0.55) | CYP19A1ALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL146771 | 0.79 | MTNR1A (0.55) | CYP19A1ALDH1A1MTNR1AMTNR1BSLC6A2 | |
| SCHEMBL3385362 | 0.78 | LMNA (0.42) | ALDH1A1HTR2AHRH1SIGMAR1 | |
| SCHEMBL3456972 | 0.78 | HRH1 (0.36) | CYP19A1HTR2AHRH1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |