Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.36 |
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302725 | 0.83 | HRH1 (0.39) | HRH1HTR2ATSHRCYP19A1HDAC3 | |
| SCHEMBL3385362 | 0.80 | LMNA (0.42) | HRH1HTR2ATAAR1CYP2D6SIGMAR1 | |
| SCHEMBL11481732 | 0.80 | POLB (0.42) | HRH1HTR2ASIGMAR1 | |
| SCHEMBL8847425 | 0.79 | HRH1 (0.39) | HRH1HTR2ACYP19A1HDAC3HDAC4 | |
| SCHEMBL8014868 | 0.78 | KCNH2 (0.47) | HTR2ACYP19A1SIGMAR1 | |
| SCHEMBL4773619 | 0.78 | CYP19A1 (0.53) | HRH1HTR2ACYP19A1SIGMAR1 | |
| SCHEMBL3316490 | 0.78 | AOC3 (0.40) | HRH1HTR2AHDAC3HDAC4HDAC1 | |
| SCHEMBL15563156 | 0.78 | POLB (0.41) | HRH1HTR2ASIGMAR1 | |
| SCHEMBL5598365 | 0.78 | TSHR (0.48) | HRH1HTR2ATSHRGABBR2GABBR1 | |
| SCHEMBL1921279 | 0.77 | SIGMAR1 (0.41) | HTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2263995-A1 | Para-tert-butylcalix[6]arenes with triacid fuctional groups in positions 2, 4 and 6, as well as supported liquid membranes and support material comprising such membranes and their use | INSTITUT DE RADIOPROTECTION ET DE SURETE NUCLEAIRE (I.R.S.N.) (FR) | 2010-12-22 | — | — | EP | disclosed |
| US-20090095681-A1 | P-TERT-BUTYLCALIX[6]ARENES WITH TRIACIDIC FUNCTIONS AT 2, 4 AND 6, SUPPORTED LIQUID MEMBRANES AND SUPPORT MATERIALS COMPRISING THE SAME AND USE THEREOF | CHELATOR (FR) | 2009-04-16 | — | — | US | disclosed |
| EP-1885682-A2 | P-TERT-BUTYLCALIX[6]ARENES WITH TRIACIDIC FUNCTIONS AT 2, 4 AND 6 SUPPORTED LIQUID MEMBRANES SUPPORT MATERIALS COMPRISING THE SAME AND USE THEREOF | CHELATOR (FR) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006123051-A2 | P-TERT-BUTYLCALIX[6]ARENES WITH TRIACIDIC FUNCTIONS AT 2, 4 AND 6 SUPPORTED LIQUID MEMBRANES SUPPORT MATERIALS COMPRISING THE SAME AND USE THEREOF | CHELATOR (FR) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090095681-A1 | P-TERT-BUTYLCALIX[6]ARENES WITH TRIACIDIC FUNCTIONS AT 2, 4 AND 6, SUPPORTED LIQUID MEMBRANES AND SUPPORT MATERIALS COMPRISING THE SAME AND USE THEREOF | TERT, SLC6A6, SLC26A3 | HRH1 1191/4885HTR2A 3452/4885TSHR 3157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.