Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763607 | 0.86 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL4772543 | 0.85 | MEN1 (0.46) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| Oxalic Acid SCHEMBL6292021 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| Oxalic Acid SCHEMBL4773633 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL4769665 | 0.84 | SMN1; SMN2 (0.43) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL4771995 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL4763566 | 0.75 | HRH3 (0.48) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| Oxalic Acid SCHEMBL4764292 | 0.75 | KDR (0.41) | ALDH1A1KDM4EMEN1KMT2ADRD2 | |
| Oxalic Acid SCHEMBL4768201 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL4791784 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020445-B1 | FUSED PYRIDINE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-6875761-B2 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. (JP) | 2005-04-05 | — | — | US | disclosed |
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. | 2004-10-14 | — | — | US | disclosed |
| US-20020013460-A1 | Condensed pyridine compound | EISAI CO., LTD | 2002-01-31 | — | — | US | disclosed |
| US-6340759-B1 | ANTISPASMODIC AGENTS | EISAI CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1020445-A1 | FUSED PYRIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013460-A1 | Condensed pyridine compound | MUSK, HTR1A, PAX3 | ALDH1A1 2989/4885KDM4E 1050/4885SMN1; SMN2 27/4885 |
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | MUSK, HTR1A, RYR1 | ALDH1A1 1071/4885KDM4E 1058/4885SMN1; SMN2 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.